Results 171 to 180 of about 103,530 (319)
The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells
Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen+29 more
wiley +1 more source
Abstract Kidney transplantation remains the therapeutic option for patients with end‐stage kidney disease. Current immunosuppressive regimens are efficient in combating acute kidney rejection. However, insights into chronic kidney allograft injury remains limited.
Bartosz Wojciuk+6 more
wiley +1 more source
Exosomes, autophagy, and cancer: A complex triad
Abstract Cancer remains one of the leading causes of death worldwide. Despite remarkable progress in prevention, diagnosis, and therapy, the incidence of certain types of cancer persists, urging the identification of clinically relevant biomarkers and the development of novel therapeutic strategies to improve clinical outcomes and overcome treatment ...
María Guerra‐Andrés+2 more
wiley +1 more source
miRNAs and lncRNAs in vascular injury and remodeling [PDF]
Xiaowei Song+3 more
openalex +1 more source
LncRNA SNHG4 promotes osteosarcoma proliferation and migration by sponging miR‐377‐3p
Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023.
wiley +1 more source
A Comprehensive Review on RNA Subcellular Localization Prediction [PDF]
The subcellular localization of RNAs, including long non-coding RNAs (lncRNAs), messenger RNAs (mRNAs), microRNAs (miRNAs) and other smaller RNAs, plays a critical role in determining their biological functions. For instance, lncRNAs are predominantly associated with chromatin and act as regulators of gene transcription and chromatin structure, while ...
arxiv
Decoding the noncoding: Prospective of lncRNA-mediated innate immune regulation [PDF]
Zhonghan Li, Tariq M. Rana
openalex +1 more source