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LncRNA MALAT1 Promotes Ulcerative Colitis by Upregulating lncRNA ANRIL
Digestive Diseases and Sciences, 2020LncRNA MALAT1 contributes to the inflammatory responses induced by lipopolysaccharides (LPS), which shares similar pathogenesis with ulcerative colitis (UC), indicating the potential involvement of MALAT1 in UC.Expression of MALAT1 and lncRNA ANRIL in both UC patients and healthy controls was analyzed by RT-qPCR. ROC curve analysis was used to evaluate
Mingyan Zhu, Jian Xie
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Clinica Chimica Acta, 2019
Ovarian cancer is one of the most common gynecologic malignancies and has a poor prognosis. Recently, long noncoding RNAs (lncRNAs) have been identified as key regulators of cancer development. Studies have shown that the dysregulation of lncRNAs is frequently observed in ovarian cancer and greatly contributes to malignant phenotypical changes. In this
Jin-yan Wang, Ai-qing Lu, Li-juan Chen
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Ovarian cancer is one of the most common gynecologic malignancies and has a poor prognosis. Recently, long noncoding RNAs (lncRNAs) have been identified as key regulators of cancer development. Studies have shown that the dysregulation of lncRNAs is frequently observed in ovarian cancer and greatly contributes to malignant phenotypical changes. In this
Jin-yan Wang, Ai-qing Lu, Li-juan Chen
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WIREs RNA, 2016
The diversity of long non‐coding RNAs (lncRNAs) in the human transcriptome is in stark contrast to the sparse exploration of their functions concomitant with their conservation and evolution. The pervasive transcription of the largely non‐coding human genome makes the evolutionary age and conservation patterns of lncRNAs to a topic of interest.
Anne Nitsche, Peter F. Stadler
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The diversity of long non‐coding RNAs (lncRNAs) in the human transcriptome is in stark contrast to the sparse exploration of their functions concomitant with their conservation and evolution. The pervasive transcription of the largely non‐coding human genome makes the evolutionary age and conservation patterns of lncRNAs to a topic of interest.
Anne Nitsche, Peter F. Stadler
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2015
All living organisms sense and respond to harmful changes in their intracellular and extracellular environment through complex signaling pathways that lead to changes in gene expression and cellular function in order to maintain homeostasis. Long non-coding RNAs (lncRNAs), a large and heterogeneous group of functional RNAs, play important roles in ...
Saba, Valadkhan +1 more
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All living organisms sense and respond to harmful changes in their intracellular and extracellular environment through complex signaling pathways that lead to changes in gene expression and cellular function in order to maintain homeostasis. Long non-coding RNAs (lncRNAs), a large and heterogeneous group of functional RNAs, play important roles in ...
Saba, Valadkhan +1 more
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Science Signaling, 2015
The interaction of a lncRNA with the complex of NF-κB and its inhibitor IκB prevents phosphorylation-mediated release and activation of NF-κB.
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The interaction of a lncRNA with the complex of NF-κB and its inhibitor IκB prevents phosphorylation-mediated release and activation of NF-κB.
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Mechanisms of lncRNA Biogenesis as Revealed by Nascent Transcriptomics
Nature Reviews Molecular Cell Biology, 2022Nicholas Jarvis Proudfoot +1 more
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Structural Variation in COOLAIR lncRNA Driven by Cold
Nature Reviews Molecular Cell Biology, 2022Lisa Heinke
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The lncRNA39896–miR166b–HDZs Module Affects Tomato Resistance to Phytophthora infestans
Journal of Integrative Plant Biology, 2022Yushi Luan, Jun Meng, Yinhua Chen
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