Results 181 to 190 of about 144,315 (291)

A novel deep learning-driven framework for improving lncRNA comprehensive annotation with LncADeep 2.0. [PDF]

open access: yesBioinformatics
Zhou Y   +7 more
europepmc   +1 more source

Putative involvement of lncRNA, miRNA, and mRNA‐mediated ceRNA network regulation in drought priming to enhance drought tolerance in Nicotiana tabacum

open access: yesAnnals of Applied Biology, EarlyView.
Drought priming increased the tolerance of Nicotiana tabacum to severe, recurring drought stress by modulating the expression of stress‐related genes via long non‐coding RNAs (lncRNAs), which acted as competing endogenous RNAs (ceRNAs) for microRNAs (miRNAs) and messenger RNAs (mRNAs).
Fatma Aydinoglu, Elif Yalvac
wiley   +1 more source

Evaluating putative lncRNA‐mediated ceRNA regulatory network involving miR396 and miR319 in maize leaf growth under Fusarium verticillioides infection

open access: yesAnnals of Applied Biology, EarlyView.
The final leaf length of maize (Zea mays) was reduced due to the pathogenic fungus Fusarium verticillioides infection as a result of increased expression of miR396 in the elongation zone and decreased expression of miR319 in the mature zone of maize leaves, leading to antagonistic regulation of the expression of the GRF15 and TCP38, respectively ...
Erdem Emre Deligoz, Fatma Aydinoglu
wiley   +1 more source

Oral Immunotherapy Induces Shift in lncRNA Expression Modulating Allergen‐Specific Immune Responses

open access: yesAllergy, EarlyView.
We used PBMC transcriptome from 50 hen's egg‐allergic patients to study the role of lncRNA in OIT. Positive correlation was found between 17 lncRNAs and the IL‐4/IL‐13 pathway in vivo, and the expression of the selected lncRNA aligned with CXCL8 upon PBMC egg‐restimulation.
Olivia Liong   +5 more
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

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