Three closely linked X‐chromosomal genes potentially control sex determination in Cannabis sativa
New Phytologist, Volume 251, Issue 1, Page 505-522, July 2026.Summary Sex determination mechanisms in dioecious plants remain poorly understood yet offer an excellent model system to study genetic changes underlying morphological evolution. We investigated the genetic basis of sex determination in Cannabis sativa, combining quantitative trait locus mapping in a segregating population, comparative transcriptomics ...
Matteo Toscani +8 more
wiley +1 more source
LncRNA as a diagnostic marker for rheumatoid arthritis: a systematic review and meta-analysis. [PDF]
Korean J Intern MedLuo LL, Chen YT, Xu YN, Lu M, Liu XD.
europepmc +1 more source
International Journal of Cancer, Volume 158, Issue 12, Page 3268-3278, 15 June 2026.What's new? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt +6 more
wiley +1 more source
Novel cuproptosis related long non-coding RNA signature in oral squamous cell carcinoma prognosis and immunotherapy. [PDF]
Discov OncolSur S.
europepmc +1 more source
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.During the development of OA, elevated RORα in chondrocytes inhibits β‐catenin degradation in the cytoplasm by activating the Wnt/β‐catenin signaling pathway. When β‐catenin protein accumulates excessively in the cytoplasm, it is transferred to the nucleus and binds to the cytosolic TCF/LEF transcriptional complex, which activates downstream target ...
Ruijue Zhu +9 more
wiley +1 more source
Super-enhancer-driven ITGB2-AS1 promotes ovarian cancer progression by binding to IQGAP1. [PDF]
Transl OncolWang Y, Li P.
europepmc +1 more source
Compartment‐Specific Immune Remodeling of Renal Aging With C1q‐Associated Podocyte Activation
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Aging repatterns the renal immune response in a compartment‐specific manner, distinct from chronic kidney disease (CKD) adaptation. Glomerular aging features C1q‐associated podocyte activation and macrophage engagement, whereas tubulointerstitial aging is marked by B‐cell aggregation and tertiary lymphoid structure expansion.
Ju‐Young Moon +10 more
wiley +1 more source
[Expression of Concern] lncRNA HOTTIP facilitates osteosarcoma cell migration, invasion and epithelial-mesenchymal transition by forming a positive feedback loop with c-Myc. [PDF]
Oncol LettTang Y, Ji F.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 6, Page 1115-1131, June 2026.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source