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Clinica Chimica Acta, 2022
Osteoarthritis (OA) is a progressive joint disease that affects millions of older adults around the world. With increasing rates of incidence and prevalence worldwide, OA has become an enormous global socioeconomic burden on healthcare systems. Long non-coding ribonucleic acids (lncRNAs), essential functional molecules in many biological processes, are
Okuyan, Hamza Malik, Begen, Mehmet A.
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Osteoarthritis (OA) is a progressive joint disease that affects millions of older adults around the world. With increasing rates of incidence and prevalence worldwide, OA has become an enormous global socioeconomic burden on healthcare systems. Long non-coding ribonucleic acids (lncRNAs), essential functional molecules in many biological processes, are
Okuyan, Hamza Malik, Begen, Mehmet A.
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lncRNAs in mesenchymal differentiation
American Journal of Physiology-Cell Physiology, 2022In recent years, technological advances have revealed a large potential number of long noncoding RNAs (lncRNAs). Findings recognize lncRNAs as orchestrating molecules in a wide range of processes, at the transcriptional and posttranscriptional levels, although fewer studies address function. For differentiation, which consists of rearrangements in the
Marcela Angelica, De la Fuente-Hernandez +3 more
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LncRNA MALAT1 Promotes Ulcerative Colitis by Upregulating lncRNA ANRIL
Digestive Diseases and Sciences, 2020LncRNA MALAT1 contributes to the inflammatory responses induced by lipopolysaccharides (LPS), which shares similar pathogenesis with ulcerative colitis (UC), indicating the potential involvement of MALAT1 in UC.Expression of MALAT1 and lncRNA ANRIL in both UC patients and healthy controls was analyzed by RT-qPCR. ROC curve analysis was used to evaluate
Mingyan Zhu, Jian Xie
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Clinica Chimica Acta, 2015
Long noncoding RNAs are emerging as new mediators of tumorigenesis by virtue of their various functions and their capacity to induce different mechanisms as a result of their wide spectrum of interactions. They play critical roles in a broad range of cellular processes including regulation of gene expression, imprinting, chromatin modification ...
Mustafa, Isin, Nejat, Dalay
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Long noncoding RNAs are emerging as new mediators of tumorigenesis by virtue of their various functions and their capacity to induce different mechanisms as a result of their wide spectrum of interactions. They play critical roles in a broad range of cellular processes including regulation of gene expression, imprinting, chromatin modification ...
Mustafa, Isin, Nejat, Dalay
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International Immunopharmacology, 2018
Long noncoding RNAs (lncRNAs) are emerging as crucial regulators of gene expression in immune system. It has been reported that lncRNAs participate in regulation of immune responses through both transcriptional and post-transcriptional mechanisms. In this review, we summarize the molecular functions of lncRNAs and discuss their binding to DNA, RNA and ...
Xue Li, Nan Li
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Long noncoding RNAs (lncRNAs) are emerging as crucial regulators of gene expression in immune system. It has been reported that lncRNAs participate in regulation of immune responses through both transcriptional and post-transcriptional mechanisms. In this review, we summarize the molecular functions of lncRNAs and discuss their binding to DNA, RNA and ...
Xue Li, Nan Li
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LncRNA NKILA Inhibits Retinoblastoma by Downregulating lncRNA XIST
Current Eye Research, 2019Purpose: Although retinoblastoma is rare but can be deadly in some severe cases. To find novel therapeutic targets for retinoblastoma, we explored the potential role of lncRNA NKILA in retinoblastoma. Results: We found that, comparing to healthy controls, NKILA was downregulated, while lncRNA XIST was upregulated in plasma of retinoblastoma patients ...
Xueman, Lyu +4 more
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Prostate cancer-associated lncRNAs
Cancer Letters, 2018Long non-coding RNA (LncRNA) is defined as an RNA transcript that does not encode any protein, with a length longer than 200 nt. Based on the recent advances in high-throughput sequencing techniques, a large number of lncRNAs have been characterized as functional transcripts that play important roles in various biological processes as well as ...
Yuichi, Mitobe +3 more
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2021
Drugs have been discovered since ancient times, with the use of each plant for a medical purpose that mainly aimed at pain relief. Over time, the use became recreational, while it was not long before the processing of substances led not only to stronger results, but also to an ever-evolving pathological condition. Over the centuries and the development
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Drugs have been discovered since ancient times, with the use of each plant for a medical purpose that mainly aimed at pain relief. Over time, the use became recreational, while it was not long before the processing of substances led not only to stronger results, but also to an ever-evolving pathological condition. Over the centuries and the development
openaire +1 more source