Results 51 to 60 of about 39,827 (164)
, 2023 Skin is the first line of the body to resist pathogen invasion. A potentially fatal infection may result from problems with wound healing. Small molecule drugs like astragaloside IV (AS‐IV) show pro‐healing activities, but the mechanisms are not fully ...
Li‐Ze Zhang +3 more
core +1 more source
British Journal of Pharmacology, EarlyView.Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff +3 more
wiley +1 more source
The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis
The FEBS Journal, EarlyView.H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo +8 more
wiley +1 more source
, 2023 There is growing evidence that long non-coding RNAs (lncRNAs) are significant contributors to the epigenetic mechanisms implicated in the emergence, progression and metastasis of the colorectal cancer (CRC), but many remain underexplored. A novel lncRNA
Ting Zhan (8701923)
core +1 more source
Cell & Bioscience, 2019 Objective To investigate the mechanism of LncRNA H19 in Th17 cell differentiation and endometrial stromal cells (ESCs) proliferation in endometriosis (EMS).
Zheying Liu +8 more
doaj +1 more source
Long non-coding RNA H19 promotes glioma cell invasion by deriving miR-675. [PDF]
PLoS ONE, 2014 H19 RNA has been characterized as an oncogenic long non-coding RNA (lncRNA) in breast and colon cancer. However, the role and function of lncRNA H19 in glioma development remain unclear.
Yan Shi +8 more
doaj +1 more source
Understanding exosomes in diabetic wound healing
Periodontology 2000, EarlyView.Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad +4 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Estrogen Regulates the Expression and Function of lncRNA-H19 in Ectopic Endometrium
International Journal of Women's Health, 2022 Songping Liu,1,2,* Junjun Qiu,3,* Xiaoyan Tang,3,* Qinmei Li,1 Wei Shao1 1Department of Obstetrics and Gynecology, Jinshan Hospital of Fudan University, Shanghai, People’s Republic of China; 2Department of Obstetrics and Gynecology, Zhenjiang ...
Liu S, Qiu J, Tang X, Li Q, Shao W
doaj
An emerging potential therapeutic target for osteoporosis: LncRNA H19/miR-29a-3p axis
European Journal of Histochemistry, 2020 Osteoporosis (OP) is a complex systemic disease characterized by a loss of bone density, leading to bone fragility and an increase risk of fractures of the hip, spine and wrist. The clinical therapeutic effect is still far from satisfactory.
Ziqi Li +6 more
doaj +1 more source