Results 71 to 80 of about 39,827 (164)

Identification of lncRNAs in Breast Cancer Through Bioinformatics Analysis: Implications for Pathogenesis and Prognostic Significance

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Objective Breast cancer (BC) is a disease with a subtle onset, often diagnosed late, and has a high mortality rate. This study aimed to identify long non‐coding RNAs (lncRNAs) linked to BC as prognostic markers using bioinformatics and initial experiments, explore their regulatory pathways, and assess their expression and prognostic ...
Yuhan Zheng, Xinggui Chen, Xuan Liu, Yijin Zhou, Pei Yang, Shuhui Li   +5 more
wiley   +1 more source

Long non-coding RNA H19 regulates E2F1 expression by competitively sponging endogenous miR-29a-3p in clear cell renal cell carcinoma

Cell & Bioscience, 2017
Background Numerous recent studies indicate that the long non-coding RNAs (lncRNAs) are frequently abnormal expressed and take critical roles in many cancers.
Haowei He, Nana Wang, Xiaoming Yi, Chaopeng Tang, Dong Wang   +4 more
doaj   +1 more source

Conditional depletion of macrophages ameliorates cholestatic liver injury and fibrosis via lncRNA-H19

Cell Death and Disease, 2021
Although macrophages are recognized as important players in the pathogenesis of chronic liver diseases, their roles in cholestatic liver fibrosis remain incompletely understood.
Xinbei Tian, Ying Wang, Ying Lu, Weipeng Wang, Jun Du, Shanshan Chen, Huiping Zhou, Wei Cai, Yongtao Xiao   +8 more
doaj   +1 more source

Harnessing microbial metabolism and nutrition to target the gut–mammary axis for better livestock production and health

iMetaOmics, Volume 3, Issue 3, September 2026.
The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou, Cheng Guo, Mahmoud M. Abdelsattar, Ahmad R. Musa, Mequanint Biks, Abdullahi A. Musa, Shahnaz Rahman, Abera Teshome Aleli, Pei Zhong, Jiawei Zhang, Junwei Cui, Xiyan Kou, Qingyuan Yu, Caijuan Yue, Qin Li, Dan Zhang, Zixuan Peng, Ao Ren, Ziqi Tian, Ziqi Liu, Yaona Zhang, Lili Zhang, Dina Karmallah, Naifeng Zhang, Tao Ma, Yan Tu, Qiyu Diao, Guijie Zhang, Xiaofeng Xu, Yanliang Bi   +29 more
wiley   +1 more source

LncRNA H19 regulates ID2 expression through competitive binding to hsa-miR-19a/b in acute myelocytic leukemia

, 2017
Acute myelocytic leukemia (AML) is the most common type of acute leukemia. Long non-coding RNAs (lncRNAs) serve an important role in regulating gene expression through chromatin modification, transcription and post-transcriptional processing.
Xiao-Su Zhao, Wei Zhang, Chen, Xiao Fan, Zhen-Zhen Zhang, Zou, Yan Fen, Zhang, Wei, Hui-Zhen Jia, Zhao, Tong Feng, Zhao, Tong-Feng, Jia, Hui Zhen, Tong-Feng Zhao, Zhao, Xiao Su, Jia, Hui-Zhen, Jun Wan, Yan-Fen Zou, Wan, Jun, Zhang, Zhen Zhen, Chen, Xiao-Fan, Xiao-Fan Chen, Zhang, Zhen-Zhen, Zhao, Xiao-Su, Zou, Yan-Fen   +21 more
core   +1 more source

DataSheet5_Association of lncRNA H19 polymorphisms with cancer susceptibility: An updated meta-analysis based on 53 studies.PDF

, 2022
The association between polymorphisms in lncRNA H19 and cancer susceptibility remains to be inconsistent. This study aimed to provide a more precise estimation of the relationship between lncRNA H19 polymorphisms and the risk of cancer based on all ...
Yingying Yuan (9674249), Yachun Wang (155485), Yue Zhao (186573), Zheng Li (26302), Wei Wang (17594), Yungang Han (13301760), Wenbo Li (669721), Xiaodong Niu (11708913), Meijin Cheng (14255828), Jiao Tan (10782800)   +9 more
core   +1 more source

Long Noncoding RNA-H19 Contributes to Atherosclerosis and Induces Ischemic Stroke via the Upregulation of Acid Phosphatase 5

Frontiers in Neurology, 2019
Objective: Atherosclerosis is closely associated with ischemic stroke, and long noncoding RNA-H19 (lncRNA-H19) might be a potential target for treating atherosclerosis.
Yujing Huang, Liping Wang, Ying Mao, Guangxian Nan   +3 more
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions

, 2020
Activation of hepatic macrophages represents the critical driving force to promote cholestatic liver injury. Exosomes, as important small extracellular vesicles released by almost all types of cells, contribute to intercellular communication.
Weiwei Zhu, Hang Yang, Emily C. Gurley, Huiping Zhou, Xuan Wang, Weidong Chen, Xiaojiaoyang Li, Yanyan Wang, Derrick Zhao, Runping Liu, Phillip B. Hylemon   +10 more
core   +1 more source

DataSheet4_Association of lncRNA H19 polymorphisms with cancer susceptibility: An updated meta-analysis based on 53 studies.PDF

, 2022
The association between polymorphisms in lncRNA H19 and cancer susceptibility remains to be inconsistent. This study aimed to provide a more precise estimation of the relationship between lncRNA H19 polymorphisms and the risk of cancer based on all ...
Yingying Yuan (9674249), Yachun Wang (155485), Yue Zhao (186573), Zheng Li (26302), Wei Wang (17594), Yungang Han (13301760), Wenbo Li (669721), Xiaodong Niu (11708913), Meijin Cheng (14255828), Jiao Tan (10782800)   +9 more
core   +1 more source