Results 141 to 150 of about 79,026 (218)

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

Identification of lncRNAs in Breast Cancer Through Bioinformatics Analysis: Implications for Pathogenesis and Prognostic Significance. [PDF]

Cancer Med
Zheng Y, Chen X, Liu X, Zhou Y, Yang P, Li S.   +5 more
europepmc   +1 more source

Emerging Roles of PSTPIP2 in Autoimmunity: From Mechanism to Therapeutic Implications

Immunology, EarlyView.
PSTPIP2 acts as a key brake on myeloid inflammation by suppressing IL‐1β‐driven signalling, macrophage dysregulation and inflammation‐associated bone remodelling. Its emerging roles in CRMO/CMO, rheumatoid arthritis, SAPHO syndrome and bullous pemphigoid support its potential as a biomarker and therapeutic target.
Erdong Zhang, Fengyu Liu, Yongle Wei, Guoqiang Li, Liujie Zheng, Lin Jin, Feng Luan, Yingze Zhang, Ling Wang, Zhiyong Hou   +9 more
wiley   +1 more source

Noncoding RNAs as novel diagnostic biomarkers for diabetic retinopathy: A systematic review and meta‐analysis

Journal of Diabetes Investigation, EarlyView.
The systematic review and meta‐analysis (Embase, PubMed, and Web of Science; up to August 2025) evaluated circulating noncoding RNAs (ncRNAs) as noninvasive early diagnostic biomarkers for diabetic retinopathy (DR). From 17 articles (24 studies, 1,983 DR patients vs 1,437 controls), a random‐effects model yielded pooled sensitivity of 0.81, specificity
Ting Zhang, Donghong Xu
wiley   +1 more source

Whole-transcriptome dynamics reveal distinct regulatory networks during sugar beet vernalization. [PDF]

Front Plant Sci
Zhou X, Zhong Z, Wang L, Ku Y, Wu Z, Pi Z.   +5 more
europepmc   +1 more source

Evaluating integrative strategies for incorporating phenotypic features in spatial transcriptomics

Journal of Microscopy, EarlyView.
Abstract The key advantage of spatial transcriptomics (ST) technologies lies in the spatial domain: these techniques not only offer an unprecedented opportunity to interrogate intact biological samples in a spatially informed manner, but also set the stage for integration with other imaging‐based modalities.
Levin M Moser, Ahmad Kamal Hamid, Esteban Miglietta, Nodar Gogoberidze, Beth A Cimini   +4 more
wiley   +1 more source

Expression Landscape and Circadian Regulation of lncRNAs in the Kidney. [PDF]

Acta Physiol (Oxf)
Wigger L, Durussel F, Auberson M, Firsov D, Bignon Y.   +4 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Long Noncoding RNAs (lncRNAs) as Biomarkers of Prognosis in TNBC and Non-TNBC Breast Cancer Patients. [PDF]

Int J Mol Sci
Acencio ML, Wang X, Mangone FRR, Carraro DM, Llera AS, Abdelhay ESFW, Artagaveytia N, Daneri-Navarro A, Reis EM, Sanches L, Chammas R, Podhajcer OL, Velazquez C, Nagai MA.   +13 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source