Results 21 to 30 of about 73,797 (157)

Epigenetic Mechanisms in Vascular Inflammation: Modulation of Endothelial Adhesion Molecules and Endothelium-Leukocyte Adhesion

open access: yesFrontiers in Bioscience-Landmark, 2023
The endothelium, an essential component of the vascular system, plays a critical role in the inflammatory response. Under pro-inflammatory stimuli, endothelial cells undergo activation and dysfunction, leading to the release of inflammatory mediators and
Nadia Calabriso   +5 more
doaj   +1 more source

LncRNA GAS8‐AS1 downregulates lncRNA NEAT1 to inhibit glioblastoma cell proliferation [PDF]

open access: yesBrain and Behavior, 2021
Abstract Background LncRNA GAS8‐AS1 has been reported to participate in several types of cancer, while its role in glioblastoma (GBM) is unknown. In the present study, we aimed to investigate the function of GAS8‐AS1 in GBM and the underlying mechanisms.
Xiaoming Wu   +3 more
openaire   +3 more sources

Nine Pyroptosis-Related lncRNAs are Identified as Biomarkers for Predicting the Prognosis and Immunotherapy of Endometrial Carcinoma

open access: yesInternational Journal of General Medicine, 2021
Deku Liang,1,2 Min Hu,1 Qin Tang,1 Mao Huang,1 Liangdan Tang1 1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of Obstetrics and Gynecology ...
Liang D, Hu M, Tang Q, Huang M, Tang L
doaj  

The function of non-coding RNAs in idiopathic pulmonary fibrosis

open access: yesOpen Medicine, 2021
Non-coding ribonucleic acids (ncRNAs) are a diverse group of RNA molecules that are mostly not translated into proteins after transcription, including long non-coding RNAs (lncRNAs) with longer than 200 nucleotides non-coding transcripts and microRNAs ...
Zhang Hui   +5 more
doaj   +1 more source

LncRNA PCAT-1 Reduces Sensitivity of Cervical Carcinoma Cells to Cisplatin by Regulating STAT3 and PTEN Expression

open access: yesZhongliu Fangzhi Yanjiu, 2021
Objective To investigate the role and regulatory mechanism of lncRNAs PCAT-1 in the sensitivity of cervical cancer cells to DDP. Methods The expressions of PCAT-1 in human cervical cancer cell lines (HeLa and SiHa) and DDP-resistant cell lines (HeLa/DDP ...
MAO Xuebao, WANG Xiuhong
doaj   +1 more source

LncRNA, miRNA and lncRNA-miRNA interaction in viral infection

open access: yesVirus Research, 2018
Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important role in both normal biological activity and pathological processes such as viral infection and tumorigenesis. LncRNAs and miRNAs are the most important elements of ncRNAs and function as vital regulatory elements.
Linlin, Chen, Yan, Zhou, Hongjun, Li
openaire   +2 more sources

LncRNAs in Stem Cells [PDF]

open access: yesStem Cells International, 2016
Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a special position in cell biology and Biomedicine, and emerging results show that multiple ncRNAs play essential roles in stem cells. We discuss some of the known ncRNAs in stem cells such as embryonic stem cells, induced pluripotent stem cells ...
Shanshan Hu, Ge Shan
openaire   +3 more sources

Mechanisms of early- and late-feathering in Qingyuan partridge chickens

open access: yesBiotechnology & Biotechnological Equipment, 2019
Long non-coding RNAs (lncRNAs) are important in feather development and feathering patterns, but few studies on this subject have been conducted in chickens.
Li Ning Su   +5 more
doaj   +1 more source

Construction and analysis of lncRNA-lncRNA synergistic networks to reveal clinically relevant lncRNAs in cancer

open access: yesOncotarget, 2015
Long non-coding RNAs (lncRNAs) play key roles in diverse biological processes. Moreover, the development and progression of cancer often involves the combined actions of several lncRNAs. Here we propose a multi-step method for constructing lncRNA-lncRNA functional synergistic networks (LFSNs) through co-regulation of functional modules having three ...
Yongsheng, Li   +7 more
openaire   +3 more sources

Aberrant expression of long non-coding RNAs (lncRNAs) is involved in brain glioma development

open access: yesArchives of Medical Science, 2019
Introduction Aberrant expression of long non-coding RNAs (lncRNAs) has been implicated in various diseases, including cancer. However, little is known about lncRNAs in human brain gliomas.
Yi Ding   +7 more
doaj   +1 more source

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