Results 41 to 50 of about 117,416 (307)

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

LncRNAs in Stem Cells [PDF]

Stem Cells International, 2016
Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a special position in cell biology and Biomedicine, and emerging results show that multiple ncRNAs play essential roles in stem cells. We discuss some of the known ncRNAs in stem cells such as embryonic stem cells, induced pluripotent stem cells ...
Shanshan Hu, Ge Shan
openaire   +3 more sources

Aberrant expression of long non-coding RNAs (lncRNAs) is involved in brain glioma development

Archives of Medical Science, 2019
Introduction Aberrant expression of long non-coding RNAs (lncRNAs) has been implicated in various diseases, including cancer. However, little is known about lncRNAs in human brain gliomas.
Yi Ding, Xinfa Wang, Junchen Pan, Minjun Ji, Zhengxiang Luo, Penglai Zhao, Yansong Zhang, Gang Wang   +7 more
doaj   +1 more source

Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR [PDF]

, 2016
Long non-coding RNAs (lncRNAs) form a new class of RNA molecules implicated in various aspects of protein coding gene expression regulation. To study lncRNAs in cancer, we generated expression profiles for 1707 human lncRNAs in the NCI60 cancer cell line
Derveaux, Stefaan, Hellemans, Jan, Lefever, Steve, Mestdagh, Pieter, Vandesompele, Jo, Volders, Pieter-Jan   +5 more
core   +2 more sources

Noncoder : a web interface for exon array-based detection of long non-coding RNAs [PDF]

, 2012
Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas, Gellert, Pascal, Ponomareva, Yuliya, Uchida, Shizuka   +3 more
core   +1 more source

The influence of lncRNA expression dysregulation on predicting celiac diseases among patients with Hashimoto's thyroiditis [PDF]

African Journal of Gastroenterology and Hepatology
Aim: the study aimed to investigate lncRNA IFNG-AS1 in Hashimoto’s thyroiditis (HT) and to evaluate its predictive and diagnostic values of Celiac disease (CD) among patients with HT.
Nearmeen Rashad, Mohamed Wahba, Abdelmonem Elshamy, Manar Soliman, Marwa Hussien, Ahmad Sallam, Amr EL Hawary   +6 more
doaj   +1 more source

Cellular and molecular basis of thyroid autoimmunity

European Thyroid Journal, 2023
Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The two major clinical manifestations of AITD are Graves’ disease and Hashimoto’s thyroiditis (HT).
Joanna Bogusławska, Marlena Godlewska, Ewa Gajda, Agnieszka Piekiełko-Witkowska   +3 more
doaj   +1 more source

Angiotensin-(1–7) Analogue AVE0991 Modulates Astrocyte-Mediated Neuroinflammation via lncRNA SNHG14/miR-223-3p/NLRP3 Pathway and Offers Neuroprotection in a Transgenic Mouse Model of Alzheimer’s Disease

Journal of Inflammation Research, 2021
Rui Duan,1,* Si-Yu Wang,1,* Bin Wei,1 Yang Deng,2 Xin-Xin Fu,2 Peng-Yu Gong,1 Yan E,1 Xiao-Jin Sun,2 Hai-Ming Cao,1 Jian-Quan Shi,1 Teng Jiang,1 Ying-Dong Zhang1,2 1Department of Neurology, Nanjing First Hospital, Nanjing Medical University ...
Duan R, Wang SY, Wei B, Deng Y, Fu XX, Gong PY, E Y, Sun XJ, Cao HM, Shi JQ, Jiang T, Zhang YD   +11 more
doaj  

Regulation of lncRNA expression

Cellular and Molecular Biology Letters, 2014
AbstractLong non-coding RNAs (lncRNAs) are series of transcripts with important biological functions. Various diseases have been associated with aberrant expression of lncRNAs and the related dysregulation of mRNAs. In this review, we highlight the mechanisms of dynamic lncRNA expression.
Wu, Zhuomin, Liu, Xiaoxia, Liu, Li, Deng, Houliang, Zhang, Jingjing, Xu, Qian, Cen, Bohong, Ji, Aimin   +7 more
openaire   +2 more sources

Exploring the Molecular Mechanism of lncRNA–miRNA–mRNA Networks in Non-Syndromic Cleft Lip with or without Cleft Palate

International Journal of General Medicine, 2021
Xiangpu Wang, Siyuan Guo, Xinli Zhou, Yupei Wang, Ting Zhang, Renji Chen Department of Oral and Maxillofacial Plastic and Trauma Surgery, Center of Cleft Lip and Palate Treatment, Beijing Stomatological Hospital, Capital Medical University, Beijing ...
Wang X, Guo S, Zhou X, Wang Y, Zhang T, Chen R   +5 more
doaj