Results 21 to 30 of about 76,795 (267)

Insights into the mechanisms of non-coding RNAs’ implication in the pathogenesis of Alzheimer’s disease

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2022
Non-coding RNAs including long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are implicated in the regulation of gene expression at transcriptional, posttranscriptional, and epigenetic levels.
Majid Khodayi-Shahrak   +3 more
doaj   +1 more source

Functional Roles of lncRNAs in Recurrent Pregnancy Loss: A Review Study [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2023
Recurrent pregnancy loss (RPL) or recurrent miscarriage is the failure of pregnancy before 20-24 weeks that influencesaround 2-5% of couples. Several genetic, immunological, environmental and physical factors may influenceRPL.
Shirin Azizidoost   +7 more
doaj   +1 more source

Extracellular RNA in systemic lupus erythematosus [PDF]

open access: yesExRNA, 2019
Since the discovery of extracellular RNA (exRNA), it has been shown that exRNAs play a significant role as a transducer in intercellular communication and biomarkers in various diseases.
Shanshan Liu, Dandan Wang, Yuan Liu
doaj   +1 more source

Construction and analysis of lncRNA-lncRNA synergistic networks to reveal clinically relevant lncRNAs in cancer

open access: yesOncotarget, 2015
Long non-coding RNAs (lncRNAs) play key roles in diverse biological processes. Moreover, the development and progression of cancer often involves the combined actions of several lncRNAs. Here we propose a multi-step method for constructing lncRNA-lncRNA functional synergistic networks (LFSNs) through co-regulation of functional modules having three ...
Yongsheng, Li   +7 more
openaire   +3 more sources

The lncRNA Pnky in the Brain [PDF]

open access: yesCell Stem Cell, 2015
Long noncoding RNAs (lncRNAs) influence diverse cellular processes and have been implicated in regulating stem cell properties. Now in Cell Stem Cell, Ramos et al. (2015) demonstrate that the neural-specific lncRNA Pnky regulates neuronal differentiation from neural stem cells and mediates RNA splicing through interactions with polypyrimidine tract ...
Cho, Kyung-Ok, Hsieh, Jenny
openaire   +2 more sources

The Role of LncRNAs in Uveal Melanoma [PDF]

open access: yesCancers, 2021
Uveal melanoma (UM) is an intraocular cancer tumor with high metastatic risk. It is considered a rare disease, but 90% of affected patients die within 15 years. Non-coding elements (ncRNAs) such as long non-coding RNAs (lncRNAs) have a crucial role in cellular homeostasis maintenance, taking part in many critical cellular pathways.
Paula Milán-Rois   +3 more
openaire   +3 more sources

LncRNA, miRNA and lncRNA-miRNA interaction in viral infection

open access: yesVirus Research, 2018
Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important role in both normal biological activity and pathological processes such as viral infection and tumorigenesis. LncRNAs and miRNAs are the most important elements of ncRNAs and function as vital regulatory elements.
Linlin, Chen, Yan, Zhou, Hongjun, Li
openaire   +2 more sources

Epigenetic Mechanisms in Vascular Inflammation: Modulation of Endothelial Adhesion Molecules and Endothelium-Leukocyte Adhesion

open access: yesFrontiers in Bioscience-Landmark, 2023
The endothelium, an essential component of the vascular system, plays a critical role in the inflammatory response. Under pro-inflammatory stimuli, endothelial cells undergo activation and dysfunction, leading to the release of inflammatory mediators and
Nadia Calabriso   +5 more
doaj   +1 more source

A novel autophagy-related long non-coding RNAs signature predicting progression-free interval and I-131 therapy benefits in papillary thyroid carcinoma

open access: yesOpen Medicine, 2023
This study aimed to explore the prognostic and predictive value of autophagy-related lncRNAs in papillary thyroid carcinoma (PTC). The expression data of autophagy-related genes and lncRNAs of the PTC patients were obtained from TCGA database.
Hao Jie   +5 more
doaj   +1 more source

LncRNAs in Stem Cells [PDF]

open access: yesStem Cells International, 2016
Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a special position in cell biology and Biomedicine, and emerging results show that multiple ncRNAs play essential roles in stem cells. We discuss some of the known ncRNAs in stem cells such as embryonic stem cells, induced pluripotent stem cells ...
Shanshan Hu, Ge Shan
openaire   +3 more sources

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