Results 91 to 100 of about 681,097 (293)

Crack avalanches in the three dimensional random fuse model

open access: yes, 2005
We analyze the scaling of avalanche precursors in the three dimensional random fuse model by numerical simulations. We find that both the integrated and non-integrated avalanche size distributions are in good agreement with the results of the global load
Batrouni   +21 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dynamic Load Sharing Characteristic of Planetary Transmission Considering Number of Planetary Wheel and Clearance

open access: yesJixie chuandong, 2020
In order to study the influence of the number of planetary wheel and clearance on the dynamic load sharing characteristics of the planetary transmission system, based on the lumped parameter theory, considering the factors such as error, support ...
Dong Hao, Liu Zhiyu, Liu Bo
doaj  

Fractal frontiers of bursts and cracks in a fiber bundle model of creep rupture

open access: yes, 2015
We investigate the geometrical structure of breaking bursts generated during the creep rupture of heterogeneous materials. Based on a fiber bundle model with localized load sharing we show that bursts are compact geometrical objects, however, their ...
Danku, Zsuzsa   +2 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The effect of floating spline parameter on the dynamic characteristic of encased differential planetary gear train

open access: yesScientific Reports
The load sharing performance of encased differential planetary system has a great impact on the operating performance and service life of the transmission system of the coaxial high speed helicopter.
Xiaoyu Che   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Scaling in the time-dependent failure of a fiber bundle with local load sharing

open access: yes, 1998
We study the scaling behaviors of a time-dependent fiber-bundle model with local load sharing. Upon approaching the complete failure of the bundle, the breaking rate of fibers diverges according to $r(t)\propto (T_f-t)^{-\xi}$, where $T_f$ is the ...
A. Hansen   +16 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy