Results 101 to 110 of about 2,512,085 (300)
Load Sharing with Parallel Priority Queues
Journal of Computer and System Sciences, 1995 AbstractFor maximum efficiency in a multiprocessor system the load should be shared evenly over all processors; that is, there should be no idle processors when tasks are available. The delay in a load-sharing algorithm is the larger of the maximum time that any processor can be idle before a task is assigned to it, and the maximum time that it must ...
openaire +1 more source
Load sharing for multiprocessor network nodes [PDF]
, 2003 This thesis discusses techniques for sharing the processing load among multiple processing units within systems that act as nodes in a data communications network. Load-sharing techniques have been explored in the field of computer science for many years
Kencl, Lukas
core +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Load-sharing characteristics of stenting and post-dilation in heavily calcified coronary artery. [PDF]
Sci Rep, 2023 Dong P +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Load sharing between synergistic muscles characterized by a ligand-binding approach and elastography. [PDF]
Sci Rep, 2023 Grinspan GA +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Analysis of Load Sharing Behavior in Herringbone Gears Power Branching Transmission System
, 2011 Torque-spilt transmissions are promising alternatives to the common herringbone gears for power-branching. A method was developed to analyze the load-sharing in power-branching.
Xiao Fang Yang +3 more
core +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source