Results 121 to 130 of about 2,512,085 (300)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Research of the Finite Element Analysis for Load-sharing Characteristic of Planetary Gear Train of CST

open access: yesJixie chuandong, 2018
The reliability of planetary gear transmission is mainly determined by load-sharing characteristics between the planetary wheels. The study on the load-sharing characteristics of planetary gear train is carried out based on the nonlinear finite element ...
Ji Chaoyue   +3 more
doaj  

Metaheuristic-Tuned Droop Control for PV-Based DC Microgrid Optimization Under Dynamic Load Conditions

open access: yesIEEE Access
Sustainable energy solutions from photovoltaic (PV)-based direct current (DC) microgrids (MG) encounter issues in maintaining voltage stability and power-sharing efficiency during dynamic demand fluctuation.
G. R. Prudhvi Kumar   +1 more
doaj   +1 more source

A robust load-sharing control scheme for parallel-connected multisystems

open access: yes, 2019
Parallel connection of inverters or converters is one useful method for solving the high power requirements. However, a load-sharing problem among parallel-connected systems is not an easy task, since crosstalk may take place among the subsystems.
Hur, N, Nam, K
core   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Improved FMEA Risk Assessment Based on Load Sharing and Its Application to a Magnetic Lifting System

open access: yesMachines
Failure Mode and Effects Analysis (FMEA) is a systematic risk assessment tool that effectively evaluates the safety and reliability of products prior to their deployment.
Bo Sun, Lei Wang, Jian Zhang, Ning Ding
doaj   +1 more source

A Method to Analyze and Optimize the Load Sharing of Split Path Transmissions [PDF]

open access: yes, 1996
Split-path transmissions are promising alternatives to the common planetary transmissions for rotorcraft. Heretofore, split-path designs proposed for or used in rotorcraft have featured load-sharing devices that add undesirable weight and complexity to ...
Krantz, Timothy L.
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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