Results 91 to 100 of about 754,695 (298)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Jixie qiangdu, 2021 In view of the problem that the collection of vehicle load must be completed after the prototype car is completed,and the necessary load data are often lacking in the product development stage,the standardization of load spectrum under the endurance ...
施闯闯 +5 more
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Practical theories for service life prediction of critical aerospace structural components [PDF]
A new second-order theory was developed for predicting the service lives of aerospace structural components. The predictions based on this new theory were compared with those based on the Ko first-order theory and the classical theory of service life ...
Jackson, Raymond H. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Fatigue Life Prediction of the Top Drive Gearbox Housing for 15，000 m Ultra-Deep Well Drilling Rig
Shiyou jixieDuring 15 000 m ultra-deep well drilling， the top drive gearboxes of drilling rigs need to meet the high requirements for load and reliability， and may suffer some engineering problems， such as unknown fatigue failure behavior of the housing and ...
Qiu Feng +4 more
doaj
Singular Spectrum Analysis for Forecasting of Electric Load Demand
Chemical Engineering Transactions, 2013 This paper presents the technique of Singular Spectrum Analysis (SSA) and its application for electric load forecasting purposes. SSA is a relatively new non-parametric data-driven technique developed to model non-linear and/or non-stationary, noisy time series.
Briceño, Héctor +2 more
openaire +4 more sources
Advanced composite aileron for L-1011 transport aircraft: Ground tests and flight evaluation [PDF]
A composite aileron and a metal aileron were subjected to a series of comparative stiffness and vibration tests. These tests showed that the stiffness and vibration characteristics of the composite aileron are similar to the metal aileron.
Griffin, C. F.
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source