Results 71 to 80 of about 754,695 (298)

The Load Cycle Amplitude Model: An Efficient Time-Domain Extrapolation Technique for Non-Stationary Loads in Agricultural Machinery

Agriculture
In traditional time-domain extrapolation methods, the peak over threshold (POT) model is unable to accurately identify large load cycles in the load time history, resulting in distorted extrapolation results, particularly when addressing non-stationary ...
Zihan Yang, Xuke Liu, Zhenghe Song, Hanting Liu   +3 more
doaj   +1 more source

A comparison of reliability and conventional estimation of safe fatigue life and safe inspection intervals [PDF]

Both the conventional and reliability analyses for determining safe fatigue life are predicted on a population having a specified (usually log normal) distribution of life to collapse under a fatigue test load.
Hooke, F. H.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Establishment and Analysis of Load Spectrum for Bogie Frame of High-Speed Train at 400 km/h Speed Level

Machines
The bogie frame, as one of the most critical load-bearing structures of the Electric Multiple Unit (EMU), is responsible for bearing and transmitting various loads from the car body, wheelsets, and its own installation components.
Guidong Tao, Zhiming Liu, Chengxiang Ji, Guangxue Yang   +3 more
doaj   +1 more source

Research on the vibration test load spectrum for bogie frame-mounted tractor motor based on on-track tests

机车电传动, 2023
Ignoring the effects of high-frequency signals and small-amplitude cycles that contribute little to structural fatigue damage, rainflow counting was performed on the vibration load of traction motors to generate a three-dimensional load spectrum.
LI Guoshun, GUO Lirong, CHEN Can, ZHANG Yichao, ZHANG Hongwei   +4 more
doaj  

Load Spectrum of a Car Powertrain

Journal of Middle European Construction and Design of Cars, 2012
Shrnutí Motor vozidla pracuje během jizdy v různych bodech jeho charakteristiky v zavislosti na měnicich se požadavcich na jeho moment a otačky. Zatiženi hnaciho ustroji může byt popsano prostřednictvim zatěžne mapy, nazyvane spektrum zatiženi. Članek popisuje různe formy spektra zatiženi, metody jeho ziskani (přime měřeni, simulace jizdy vozidla ...
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sentence alignment in DPC: maximizing precision, minimizing human effort [PDF]

, 2008
A wide spectrum of multilingual applications have aligned parallel corpora as their prerequisite. The aim of the project described in this paper is to build a multilingual corpus where all sentences are aligned at very high precision with a minimal human
Macken, Lieve, Paulussen, Hans, Trushkina, Julia   +2 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A Novel Load Extrapolation Method for Multiple Non-Stationary Loads on the Drill Pipe of a Rotary Rig

Machines
The drill pipe of a rotary rig is subject to the dynamic influence of non-stationary loads, including rotation torque and applied force. In order to address the challenge of simultaneously extrapolating multiple non-stationary loads, a novel ...
Haijin Wang, Zonghai Zhang, Jiguang Zhang, Yuying Shen, Jixin Wang   +4 more
doaj   +1 more source