Results 221 to 230 of about 6,457,110 (386)
Stream denitrification across biomes and its response to anthropogenic nitrate loading
Patrick J. Mulholland +34 more
semanticscholar +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Experimental study on fracture and fragmentation characteristics of laminated rocks under impact loading. [PDF]
Deng D, Li Y, Guo L, Liu G, Hua J.
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Comparative Analysis of the Spatiotemporal Evolution Patterns of Acoustic Emission Source Localization Under True Triaxial Loading and Loading-Unloading Conditions in Sandstone. [PDF]
Chen P, Yu S, Wang H, Wang Z, Li N.
europepmc +1 more source
Discussion of “Cable Movements Under Two-Dimensional Loads” [PDF]
Alan L. Jennings
openalex +1 more source

