Results 101 to 110 of about 8,834,903 (313)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

ETHNIC POLITICS AND SUSTAINABLE DEMOCRACY IN NIGERIA

open access: yesInternational Studies Journal
Since Nigeria gained independence, there has been a persistent demand for an electoral system that would foster a functional democratic process. Despite numerous reform efforts, the outcome appears to deteriorate with each successive general election ...
UKWU FELIX EMEKA
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Transformational leadership cultivating innovation and transparency in local government organisations, Thailand

open access: yesJournal of Open Innovation: Technology, Market and Complexity
This study investigates the nexus between transformational leadership (TL), organisational innovation (OI), organisational transparency (OT), and their collective impact on organisational success (LOS) within Thailand's Local Administrative Organisations
Vissanu Zumitzavan   +2 more
doaj   +1 more source

Local Administration of Minocycline Improves Nerve Regeneration in Two Rat Nerve Injury Models. [PDF]

open access: yesInt J Mol Sci, 2023
Guillemot-Legris O   +3 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Report of the Business Manager of the State Board of Administration; Other title: Business Manager's Report

open access: yes, 1916
1st (1916-1918)-[11th (1936/38)?]; Though some reports were published separately most of the reports were bound with the corresponding Biennial reports of the State Board of Administration.; Reports were approved by the State Board of ...
Kansas State Board of Administration. Business Manager
core  

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