Results 81 to 90 of about 1,369,139 (317)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Role of local self-administration in organization of local economy
Vìsnik Žitomirsʹkogo Deržavnogo Tehnologìčnogo Unìversitetu: Ekonomìčnì Nauki, 2016 The article researches the issues of studying the role of local self-administration in the organization of local economy taking into account the forms of management influence to satisfy the needs of administrative and territorial unit. On the base of
I.V. Lytvynchuk, N.O. Prokhorchuk
doaj
Canvis organitzatius i de gestió a l'Administració local: un procés lent i poc planificat
IDP, 2007 En aquest article es presenta el resultat de la recerca desenvolupada en el marc del Seminari d'e-Law i e-Government del doctorat sobre Societat de la Informació i el Coneixement de la UOC.El disseny metodològic aplicat en el treball de recerca esmentat ...
Lluís Mauri i Sellés
doaj +1 more source
Handbook for Local Government Functionaries Training
, 2011 This Handbook could serve as a useful resource for the PRIs and functionaries of the Local Self Government of Kerala on effective child governance
Dr.Peter M Raj
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Prevention, Retention & Contingency Development Reserve (PRCDR) summary of projects
, 2000 Title from covers of PDF documents (viewed June 21, 2006).; "The Institute for Local Government Administration and Rural Development (ILGARD) at Ohio University prepared this report for the Ohio Department of Job and Family Services in cooperation with ...
Ohio University. Institute for Local Government Administration and Rural Development.
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The Safety and Exploration of the Pharmacokinetics of Intrapleural Liposomal Curcumin
International Journal of Nanomedicine, 2020 Ashleigh Hocking,1 Sara Tommasi,2 Peter Sordillo,3 Sonja Klebe1,4 1Department of Anatomical Pathology, Flinders University, Adelaide, SA, Australia; 2Department of Clinical Pharmacology, Flinders University, Adelaide, SA, Australia; 3SignPath Pharma Inc,
Hocking A +3 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source