Results 71 to 80 of about 3,962,313 (317)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
QUALITY MANAGEMENT OF SERVICES OF LOCAL PUBLIC ADMINISTRATION IN THE REPUBLIC OF MOLDOVA [PDF]
One of the requirements to improve the services performed by the local public administration in the Republic of Moldova is the strategic approach of its activity.
Elena Vaculovschi, Oxana Savciuc
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
STRATEGIC MANAGEMENT – MODEL AND TOOL FOR THE DEVELOPMENT OF THE LOCAL COMMUNITIES MANAGEMENT, IN THE STATE REFORM CONTEXT [PDF]
Ever since 2007, along with the completion of the EU accession process, but also before that, our country has constantly focused on improving local government standards either through a solid and sustained reform or through public system management ...
Ana Claudia TAPARDEL
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
AntibioticsBackground/Objectives: Periprosthetic joint infections (PJIs) represent a serious complication following musculoskeletal tumor resection and megaprosthetic reconstruction.
Andreas G. Tsantes +13 more
doaj +1 more source
New Local Government System: A Step Towards Community Empowerment? [PDF]
Failure of the central/provincial governments to adequately capture local preferences and provide basic services strengthened the case for a new local government system for delivery of public services along with the authority to impose fees, taxes, user ...
Zulqarnain Hussain Anjum
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
EFFECTIVE MANAGEMENT OF CULTURAL TOURISM IN RURAL AREAS [PDF]
Cultural identity is the result of a historical development process and could become a source of wealth within the conditions of an appropriate management. One of the possibilities to materialize this relation is by it through cultural tourism. The paper
Carmen Valentina RADULESCU, Ildiko IOAN
core
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source