Results 91 to 100 of about 6,996,083 (361)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Revista Vasca de Administración Pública, 2017 Policies to improve regulation promoted by the Organisation for Economic Co-operation and Development and the European Union have recently been applied in Spain and in 2015 received a significant boost with the passing of Law 39/2015, of 1 October, on ...
Lucía Casado Casado
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
The Spanish Long-term Care System. ENEPRI Research Report No. 88, 15 June 2010 [PDF]
, 2010 Launched in January 2009, ANCIEN is a research project that runs for a 44-month period and involves 20 partners from EU member states. The project principally concerns the future of long-term care (LTC) for the elderly in Europe and addresses two ...
Fernanda Gutierrez, Maria +3 more
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Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Проблеми Законності, 2016 This article is devoted to problematic aspects of the interaction and activity coordination of territorial customs bodies of the State Fiscal Service (SFS) of Ukraine, with local state administrations and local self-government bodies.
Олексій Павлович Федотов
doaj +1 more source
The local descentralisation and the issues of municipal bonds in Romania [PDF]
This paper work analyses the connection between local financial decentralization and the potential of local public administration to sustain the local economic and social development by its own forces by taking part to the capital market.
Lacatus Carmen Maria, Mosteanu Liliana
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Projecting Progress: Are Cities on Track to Achieve the SDGs by 2030? [PDF]
, 2016 This report explores for the first time the scale of the challenge for 20 cities across the world to reach selected targets set out in the Sustainable Development Goals (SDGs).
Amina Khan +3 more
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Systemic Or Incremental Path Of Reform? The Modernization Of The Judicial System In Italy
International Journal for Court Administration, 2013 The paper presents the first results of the monitoring of the national program "Diffusion of best practices within the Italian judicial offices". The program represents the first large scale attempt at modernization of the judicial offices and focuses on
Giancarlo Vecchi
doaj +1 more source