Results 61 to 70 of about 6,996,083 (361)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Who Manages Space? Eco-DRR and the Local Community

open access: yes, 2018
The notion of ecosystem-based disaster risk reduction (DRR) has only recently emerged in Indonesia. The Indonesian central government now adopts some policies related to ecosystem-based DRR with formal commitments from local administrations.
Syarifah Aini Dalimunthe
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The future is local? Contextualizing municipal agendas on climate change in Chile

open access: yesnpj Climate Action
Social science literature on the political strategies used to mitigate and adapt to climate change has discussed the possibilities of local administrations and the multifaceted obstacles in their path.
Rosa Lehmann, Alejandra Irigoyen Rios
doaj   +1 more source

Strategic Planning in Turkish Local Administrations: How Participatory is it?

open access: yesCurrent Perspectives in Social Sciences
Strategic plans are more participatory, more responsive, more integrated and more empowering when compared to the traditional plans. It has been nearly 20 years since the Financial Management and Control Law in Turkey required public institutions ...
İhsan İkizer
doaj   +1 more source

The responsibility of officials of local administrations for violations in the sphere of land relations.

open access: yesТеорія і практика правознавства, 2016
Problem Setting. The article studies the question of responsibility of officials of local administrations for violations in the sphere of land relations. The analysis of scientific papers in the study area, considered issues related to the classification
А. С. Самородов
doaj   +1 more source

Transforming identity discourses to promote local interests during municipal amalgamations

open access: yes, 2018
This paper discusses the different ways in which local identities are used in two Dutch municipalities. Like all local administrations these Dutch municipalities have to deal with external forces by plotting their own course between closing-off and ...
K. Terlouw
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Dynamics of Everyday Life within Municipal Administrations in Francophone and Anglophone Africa

open access: yesAfrica Spectrum, 2020
Decentralisation in sub-Saharan Africa promises to build responsive institutions, hold officials to account and promote popular participation. Still, existent studies ignore the everyday interface between decentralised structures and citizens, as well as
Matthew Sabbi   +2 more
doaj   +1 more source

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