Results 71 to 80 of about 287,442 (317)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Issues of state and public administration at the regional level in the context of the subject «Innovation Management»

open access: yesJournal of Education, Health and Sport
The issue of public administration at the regional level was considered in the context of the subject «Innovative Management». The development of local self-government is of great importance for Ukraine and its population.
Inna Shorobura
doaj   +1 more source

IMPLICATIONS OF NON-REIMBURSABLE FUNDS FOR ROMANIAN LOCAL BUDGETS [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2015
Accessing non-reimbursable funds is seen as a solution for many local public authorities to develop the necessary investments for the welfare of their citizens.
DAN CONSTANTIN DĂNULEŢIU   +1 more
doaj  

Elasticities of Regional and Local Administrations Expenditures - the Portuguese case [PDF]

open access: yes, 2004
This work analyzes the evolution of real public expenditures of local and regional administrations (LRA), in Portugal, in the period after the Second World War. It also aims to estimate the elasticities associated to determinants, which explain the found
Mourão, Paulo
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The autonomy of middle managers in local education administrations: a Swedish viewpoint

open access: yesNordic Journal of Studies in Educational Policy
The focus of this article is on how the relative autonomy of middle managers is expressed in the context of local education administrations. In the Swedish education system, middle managers often constitute the link between principals at schools and ...
Linn Antonsson
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Employment Action Plan : 2002 [PDF]

open access: yes, 2002
"The UK Employment Action Plan 2002 was produced after extensive consultation and agreement across Government Departments and agencies responsible for the employment, economic and social fields.

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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