Results 71 to 80 of about 6,996,083 (361)
Should local public employment services be merged with the local social benefit administrations? [PDF]
, 2011 The German Federal government has allowed some regions (Approved Local Providers) to be solely responsible for the care of long-term unemployed. The remaining regions had to form Joint Local Agencies, where the local social benefit administrations work ...
Holzner, Christian, Munz, Sonja
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Should Local Public Employment Services be Merged with the Local Social Benefit Administrations? [PDF]
The German Federal government has allowed some regions (Approved Local Providers) to be solely responsible for the care of long-term unemployed. The remaining regions had to form Joint Local Agencies, where the local social benefit administrations work ...
Christian Holzner, Sonja Munz
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Journal of Education, Health and SportThe issue of public administration at the regional level was considered in the context of the subject «Innovative Management». The development of local self-government is of great importance for Ukraine and its population.
Inna Shorobura
doaj +1 more source
IMPLICATIONS OF NON-REIMBURSABLE FUNDS FOR ROMANIAN LOCAL BUDGETS [PDF]
Annals of the University of Petrosani: Economics, 2015 Accessing non-reimbursable funds is seen as a solution for many local public authorities to develop the necessary investments for the welfare of their citizens.
DAN CONSTANTIN DĂNULEŢIU +1 more
doaj
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
The autonomy of middle managers in local education administrations: a Swedish viewpoint
Nordic Journal of Studies in Educational PolicyThe focus of this article is on how the relative autonomy of middle managers is expressed in the context of local education administrations. In the Swedish education system, middle managers often constitute the link between principals at schools and ...
Linn Antonsson
doaj +1 more source