Results 251 to 260 of about 5,401,218 (340)

Effect of Dental Local Anesthetics on Reactive Oxygen Species: An In Vitro Study. [PDF]

Cureus
Kuroda H, Tsukimoto S, Kosai A, Komatsu N, Ouchi T, Kimura M, Sato-Boku A, Yoshida A, Yoshino F, Abe T, Shibukawa Y, Sanuki T.   +11 more
europepmc   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

A Clinical Comparative Study of Dexmedetomidine, Dexamethasone, and Clonidine as Adjuvants to Local Anesthetics in Supraclavicular Brachial Plexus Blocks. [PDF]

Cureus
Yadav UP, Agrawal J, Singh A, Goyal P.
europepmc   +1 more source

Visible Light‐Activated ZnO@CuO Coaxial Nanofibers Enhance Infected Skin Wound Healing Through Construction of p‐n Heterojunctions

Advanced Science, EarlyView.
Coaxial ZnO@CuO nanofibers activated by visible light generate ROS through enhanced photocatalytic reactions driven by improved electron hole separation in the heterojunction. This strategy enables rapid antimicrobial activity and early infection control, thereby promoting the healing of MRSA infected and diabetic wounds with biosafe and easily ...
Pengrui Dang, Han Zhao, Chenguang Zhang, Jiechen Wang, Fangyu Zhu, Qinqiu Zhong, Wenyi Zeng, Xinyuan Wang, Yumin Chen, Xu Yan, Xuliang Deng, Wenwen Liu   +11 more
wiley   +1 more source

Drug-Dependent Inhibitory Effects on Corneal Epithelium Structure, Cell Viability, and Corneal Wound Healing by Local Anesthetics. [PDF]

Int J Mol Sci
Foja S, Heinzelmann J, Hünniger S, Viestenz A, Rüger C, Viestenz A.   +5 more
europepmc   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source

Knowledge and attitudes toward anaphylaxis to local anesthetics in dental practice. [PDF]

BDJ Open
Cherrez-Ojeda I, Gallardo-Bastidas JC, Borrero GR, Mautong H, Silva PAM, Sarfraz Z, Sarfraz A, Cano L, Robles-Velasco K.   +8 more
europepmc   +1 more source

Local anesthetics as a tool for Staphylococcus spp. control: a systematic review. [PDF]

Braz J Microbiol
Barreto Bellusci H, Gervasoni LF, Peixoto IC, De Oliveira LB, de Oliveira Vieira KC, Toledo ACCG, de Oliveira CBS, Mareco EA, Naga RM, Cataneli VP, Nai GA, Winkelströter LK.   +11 more
europepmc   +1 more source

Sustained release local anesthetics for pain management: relevance and formulation approaches. [PDF]

Front Pain Res (Lausanne)
Getachew M, Tesfaye H, Yihunie W, Ayenew T, Alemu S, Dagnew EM, Biyazin Y, Abebe D, Degefu N, Abebaw A.   +9 more
europepmc   +1 more source