Results 31 to 40 of about 4,888,294 (346)

Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]

open access: yes, 2012
The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran   +4 more
core   +3 more sources

Preparação, caracterização e avaliação in vitro de microesferas de bupivacaína em excesso enantiomérico de 50% (S75-R25) Preparación, caracterización y evaluación in vitro de microesferas de bupivacaina en exceso enantiomérico de 50% (S75-R25) Preparation, characterization and in vitro evaluation of 50% enantiomeric excess bupivacaine (S75-R25)-loaded microspheres

open access: yesRevista Brasileira de Anestesiologia, 2008
JUSTIFICATIVA E OBJETIVOS: As microesferas podem ser utilizadas como um sistema de liberação controlada para prolongar a ação de anestésicos locais.
Pedro Paulo Tanaka   +6 more
doaj   +1 more source

Fusion of secretory vesicles isolated from rat liver [PDF]

open access: yes, 1978
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam   +75 more
core   +1 more source

Progress of Drug Controlled Release Systems for Local Anesthesia

open access: yesXiehe Yixue Zazhi, 2022
Reducing the drug administration times and prolonging the postoperative analgesia duration are important requirements of clinical local anesthesia. However, both local anesthetics currently used in the clinic and potentially new anesthetic drugs such as ...
LONG Kai, CAO Pei, JI Tianjiao
doaj   +1 more source

Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]

open access: yes, 2018
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek   +196 more
core   +1 more source

Adjuvants to local anesthetics: Current understanding and future trends

open access: yesWorld Journal of Clinical Cases, 2017
Although beneficial in acute and chronic pain management, the use of local anaesthetics is limited by its duration of action and the dose dependent adverse effects on the cardiac and central nervous system.
A. Swain   +3 more
semanticscholar   +1 more source

Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors

open access: yesMolecules, 2021
Local anesthetics are widely utilized in dentistry, cosmetology, and medicine. Local anesthesia is essential to providing a pain-free experience during dental and local surgeries as well as cosmetic procedures.
John K. Neubert   +9 more
doaj   +1 more source

True Allergy to Amide Local Anesthetics: A Review and Case Presentation.

open access: yesAnesthesia Progress, 2018
Adverse reactions to local anesthetics are usually a reaction to epinephrine, vasovagal syncope, or overdose toxicity. Allergic reactions to local anesthetics are often attributed to additives such as metabisulfite or methylparaben.
Babak Bina   +4 more
semanticscholar   +1 more source

Synthesis and biological activities of local anesthetics

open access: yesRSC Advances, 2019
Local anesthetics are mainly used in stomatology, ophthalmology, gynecology and surgery to temporarily relieve pain. Local anesthetics act on nerve endings or around nerve trunks, and are combined with specific sodium ion (Na+) channel sites on the nerve
Shiyang Zhou, G. Huang, Guangying Chen
semanticscholar   +1 more source

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