Results 51 to 60 of about 334,763 (303)

Further education outside the jurisdiction of local authorities in post-war England

, 2014
This paper revisits the three decades following the end of World War Two – a time when, following the 1944 Education Act, local education authorities (LEAs) were the key agencies responsible for running the education system across England.
Simmons, Robin
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

LOCAL AUTHORITIES AND ASYLUM MANAGEMENT [PDF]

The Journal of Nervous and Mental Disease, 1883
n ...
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Ranking hubs and authorities using matrix functions

, 2013
The notions of subgraph centrality and communicability, based on the exponential of the adjacency matrix of the underlying graph, have been effectively used in the analysis of undirected networks.
Estrada, Ernesto, Benzi, Michele, Klymko, Christine   +2 more
core   +1 more source

ENding HIV transmission to infants by Generating Evidence to optimise prevention and care for pregnant and postpartum Adolescent Girls and young women with HIV in Tanzania (ENGAGE): study protocol for a mixed-methods research project

BMJ Open
Introduction Sub-Saharan Africa (SSA), including Tanzania, is double-burdened with high rates of teenage pregnancy and new HIV infections among adolescent girls and young women (AGYW) aged 15–24 years.
Elin C Larsson, Hellen Siril, Bruno F Sunguya, Helga Naburi, Anna Mia Ekström, Anath Rwebembera, Andrew Mganga, Werner Maokola, Prosper Njau, Regine Unkels, Charles Festo, Michael Johnson Mahande, Roseline F Urrio, Lameck Machumi, Daima Machang’u, Brenda Simba, Theodora Mbunda, Ayoub Kibao, Michael Msangi, Anna E Kågesten, Goodluck Willey Lyatuu, Wilhellmuss I Mauka, Rashid Said Mfaume, Samwel Laizer, Honoratha Rutatinisibwa, Pascal Muhode, Mukome A Nyamhagatta   +26 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Why New Jersey Should Preserve Authority Ownership!

, 2008
This guide highlights the significant difference between public and private ownership of local water, wastewater and solid authorities and describes proactive strategies that authorities are using to provide excellent customer service.Purpose: To provide

core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Local authorities austerity management Conference proceedings, Eastbourne 23-26 March 1981

, 1981
7.35SIGLELD:f81/4141.
Local Authorities Management Services and Computer Committee, London (UK)
core