Results 71 to 80 of about 6,749,458 (277)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Effectiveness of strategy implementation using the balanced scorecard in local government authorities [PDF]
, 2013 This study focuses on two issues; first is to examine how Local Government Authorities (LGAs) implement their strategies and secondly how the Balanced Scorecard is adopted as a tool for measuring effectiveness of strategy implementation in public ...
Akerele, Emmanuel Kayode +4 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Rural Proofing for Local Authorities
, 2002 Theconcept of rural proofing, identified by the Government in its Rural WhitePaper, involves identifying whether new or existing policies will havedifferential impacts in rural areas and considering adjustments orcompensations to address these.
Caffyn, Alison, +3 more
core +3 more sources
Priority areas in municipality planning: ecosystem services, environmental impact assessments and research areas [PDF]
One Ecosystem, 2016 Thomas Palo +9 more
doaj +2 more sources
Relations between Local Authorities and Public Utilities Companies
Symphonya, 2004 The development of public utilities (supply) has led to a change in needs, thereby influencing the functions that the local public administration is asked to perform.
Flavio Gnecchi
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Local government and leisure:: A study of two local authorities and their responses to the growth of leisure [PDF]
, 1992 Local authorities have a long history of providing recreation and leisure services, but since the 1970s leisure departments have expanded with a corresponding growth in the number and importance of professional officers to run them.
Liddle, Joyce
core
Apstract: Applied Studies in Agribusiness and Commerce, 2012 One of the five basic factors in the Lengyel-type pyramid model – institutions and social capital – is essential in the economic growth of the region. Economic success however, does not only depend on participants in the economy, but on social factors ...
Andrea Emese Matkó, Csaba Berde
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source