Results 61 to 70 of about 6,749,458 (277)

Performance reporting : assessing the annual reports of Malaysian local authorities [PDF]

, 2012
There have been calls for Malaysian local authorities to be more transparent and accountable in the discharge of their functional responsibilities.
Basnan, Norida, Tooley, Stuart, Hooks, Jill   +2 more
core   +1 more source

RĂSPUNDEREA CONTRAVENȚIONALĂ A CONSILIERILOR LOCALI CONFORM REGLEMENTĂRILOR CODULUI CONTRAVENȚIONAL AL REPUBLICII MOLDOVA [PDF]

Buletinul Științific al Universității de Stat „B.P. Hasdeu” din Cahul: Științe Sociale, 2020
The legal status of the local elected person from local government, which is well defined, provides these public authorities efficient governance. Purpose of the present article is to study the normative acts concerning the one of the elements of the ...
Natalia SAITARLÎ
doaj  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

МЕСТНЫЕ СМИ И ВЛАСТЬ: ВЗАИМОДЕЙСТВИЕ В ПЕРИОД ВЫБОРОВ (НА МАТЕРИАЛЕ ПРЕССЫ МУРМАНСКОЙ ОБЛАСТИ)

Sovremennye Issledovaniâ Socialʹnyh Problem, 2015
Часть мурманских средств массовой информации находятся под контролем органов государственного управления, так как имеют в качестве учредителя муниципальные органы власти. Этот контроль особо проявляется во время проведения предвыборных кампаний, которые,
Olga Nikolajevna Ivanishcheva
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Stakeholders' perceptions on the accountability of Malaysian local authorities [PDF]

, 2010
Purpose – This paper aims to identify stakeholder perceptions on the service performance accountability of Malaysian local authorities. Design/methodology/approach – A questionnaire survey provides the primary source of information, and both descriptive ...
Hooks, Jillian, Basnan, Norida, Tooley, Stuart   +2 more
core   +1 more source

Efectos y alcance de las medidas anticrisis en el ejercicio y desenvolvimiento de la autonomía local

Revista Vasca de Administración Pública, 2013
In this article the consequences of the measures adopted by the Spanish Government are analyzed, from a legal perspective, in order to exercise and development the local autonomy principle.
Jose Ignacio Cubero Marcos
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source