Results 51 to 60 of about 12,629 (265)

Reduction an Inverse Problem to a System of Second Kind Fredholm Integral Equations with No Singularities

Journal of Mathematics, 2022
In this article, we deal with an inverse problem concerning the two-dimensional Laplace equation with local boundary conditions on a bounded region. In this problem, the goal is to reduce it into a system of Fredholm integral equations of the second kind
M. Sajjadmanesh, H. Aydi, J. Younis
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Numerical Method for Determining Potential Coefficients Matrix for Multiconductor Transmission Line [PDF]

Problems of the Regional Energetics, 2018
Consider the propagation of electromagnetic energy through multiconductor three-phase high-voltage transmission line with arbitrary number of conductors.
Patiuk V.
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

High-Order, Accurate Finite Difference Schemes for Fourth-Order Differential Equations

Axioms
This article is devoted to the study of high-order, accurate difference schemes’ numerical solutions of local and non-local problems for ordinary differential equations of the fourth order. Local and non-local problems for ordinary differential equations
Allaberen Ashyralyev, Ibrahim Mohammed Ibrahım   +1 more
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Continuous dependence of solutions to mixed boundary value problems for a parabolic equation

Electronic Journal of Differential Equations, 2008
We prove the continuous dependence, upon the data, of solutions to second-order parabolic equations. We study two boundary-value problems: One has a nonlocal (integral) condition and the another has a local boundary condition. The proofs are based on
Nikolay Iossifovich Yurchuk, Kokou Tcharie, Moussa Zakari Djibibe   +2 more
doaj  

Hyperbolic Stefan problem with nonlocal boundary conditions

Математичні Студії
In this paper, we consider problems with unknown boundaries for hyperbolic equations and systems with free boundaries with two independent variables. The boundary conditions for such equations in the linear or quasilinear cases are given in nonlocal (non-
V. Kyrylych, G. Beregova, O. Milchenko
doaj   +1 more source

Two Collocation Type Methods for Fractional Differential Equations with Non-Local Boundary Conditions

Mathematical Modelling and Analysis, 2017
A class of non-local boundary value problems for linear fractional differential equations with Caputo-type differential operators is considered. By using integral equation reformulation of the boundary value problem, we study the existence and smoothness
Mikk Vikerpuur
doaj   +1 more source