Results 81 to 90 of about 5,525,895 (318)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Population structure and genetic diversity of 25 Russian sheep breeds based on whole-genome genotyping

Genetics Selection Evolution, 2018
Background Russia has a diverse variety of native and locally developed sheep breeds with coarse, fine, and semi-fine wool, which inhabit different climate zones and landscapes that range from hot deserts to harsh northern areas.
Tatiana E. Deniskova, Arsen V. Dotsev, Marina I. Selionova, Elisabeth Kunz, Ivica Medugorac, Henry Reyer, Klaus Wimmers, Mario Barbato, Alexei A. Traspov, Gottfried Brem, Natalia A. Zinovieva   +10 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Characterization and diversity analysis of European local pig breeds and production systems under Treasure project framework

, 2016
International audienceTreasure is a multidisciplinary European Union H2020 funded project focused on the research and development of activities for the benefit of sustainable pork chains based on European local pig breeds and their production systems ...
Fontanesi, L., Nieto, R.M., Pugliese, C., Gil, J.M., Bozzi, R., Ovilo, C., Garcia-Casco, J.M., Lebret, Bénédicte, Estellé, Jordi, Oliver, M.A., Fernández, A.I.   +10 more
core   +1 more source

Diversity across major and candidate genes in European local pig breeds [PDF]

, 2018
The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds.
Kusec, G., Crovetti, J., Luca Fontanesi, Martins, José Manuel, Mercat, Marie J., Claudia Geraci (731815), Luca Fontanesi (552501), Jose P Araujo, Araujo, José Pedro, Nunez, Yolanda, Riccardo Bozzi (5296228), Garcia Casco, Juan, Juliette Riquet (480830), Óvilo, C., Rui Charneca (5289781), Maurizio Gallo (5156600), Estefania Alves (5993303), Alves, Estefania, Martin Škrlep, Muñoz, María, Bozzi, R., Savic, R., Fabián García (5993297), Marie J Mercat, Estellé, J., Alessandro Crovetti, Radovic, C., Razmaite, Violeta, Fernandez, Ana I., Martins, J.M., Núñez, Y., Jose P. Araujo (5993315), Araújo, José P., Djurkin-Kušec, Ivona, Riquet, J., Zimmer, Christoph, Karolyi, Danijel, Čedomir Radović (5296210), Araujo, J.P., Martin Škrlep (820840), Gallo, Maurizio, Jose M. Martins (5993306), Goran Kušec, Garcia Casco, Juan Maria, Alessandro Crovetti (5289730), Violeta Razmaite, Riccardo Bozzi, Danijel Karolyi, Yolanda Núñez, Crovetti, Alessandro, Candek Potokar, Marjeta, Jordi Estellé (121958), Čedomir Radović, Škrlep, M., Fontanesi, L., Kušec, Ivona Djurkin, Fernandez, Ana I, Skrlep, Martin, Martins, José M., Raquel Quintanilla, Charneca, R., Radomir Savić (5993318), Maurizio Gallo, García-Casco, J., Fabián García, Joan Tibau, Tibau, Joan, Tibau, J., Violeta Razmaite (5296219), Núñez-Moreno, Yolanda, Cristina Óvilo, Christoph Zimmer, Danijel Karolyi (5289622), Marjeta Čandek-Potokar (820843), Óvilo Martín, Cristina, Mercat, Marie J, Christoph Zimmer (3095667), Quintanilla, Raquel, Charneca, Rui, Jordi Estellé, Karolyi, D., Zimmer, C., Fontanesi, Luca, Fernández, A.I., María Muñoz (4925839), Goran Kušec (5444087), Čandek-Potokar, Marjeta, Djurkin Kušec, Ivona, Garcia, Fabian, Mercat, Marie-José, Alves, E., Cristina Óvilo (422675), Fernández, Ana Isabel, Radomir Savić, Candek-Potokar, M., Kušec, Goran, García-Casco, Juan, Muñoz, M., Juliette Riquet, Geraci, C., Mercat, M.J., Marjeta Čandek-Potokar, Munoz , Maria, Gallo, M., Ana I. Fernández (133571), Radović, Čedomir, Ivona Djurkin-Kušec, Riquet, Juliette, Juan García-Casco, Rui Charneca, Claudia Geraci, María Muñoz, Muñoz Muñoz, María, Savic, Radomir, Djurkin-Kušec, I., Jose M Martins, García, F., Estellé, Jordi, Estefania Alves, Bozzi, Riccardo, Quintanilla, R., Ana I Fernández, Geraci, Claudia, Razmaite, V., Juan García-Casco (5993300), Raquel Quintanilla (168993), Yolanda Núñez (840116), Joan Tibau (3779230), Ovilo, Cristina, Ivona Djurkin-Kušec (5993309), Marie J. Mercat (5993312)   +130 more
core   +1 more source

Experimental Characterization of Mycelium‐Based Composites Under Multiple Loading Conditions

Advanced Engineering Materials, EarlyView.
This study examines the mechanical response of mycelium‐based composites under compression, shear, and tension using mechanical testing and imaging methods. The comparison between unpressed and hot‐pressed specimens shows that hot pressing is associated with higher compression and shear stiffnesses.
Shaghayegh Elahi, Kimiya Tajik, Harvey Shaw, Matti Isakov, Sami Pajunen, Lauri Rautkari   +5 more
wiley   +1 more source

Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits

Frontiers in Genetics, 2021
Background Advances in genetic tools applied to livestock breeding has prompted research into the previously neglected breeds adapted to harsh local environments.
J. Sweet-Jones, V. Lenis, A. Yurchenko, N. Yudin, M. Swain, D. Larkin   +5 more
semanticscholar   +1 more source

Long‐Range Coordination Environment Modulates Single‐Atom Local States and Systemic Impact on CO2 Photoconversion

Advanced Functional Materials, EarlyView.
Terminal groups on Cu porphyrins modulate the electronic states of single‐atom Cu centers through a long‐range electronic effect, without altering the Cu coordination geometry. Meanwhile, a multi‐descriptor framework is established that incorporates porphyrin regulation, hybrid catalyst properties, and CO2 photoreduction capabilities.
Yi Zhang, Jintao Dong, Xiahe Chen, Xiyang Wang, Tiange Wei, Yue Zhu, Tai‐Sing Wu, Yun‐Fang Yang, Shao‐Yuan Leu, Keke Wang, Yuanbin She, Huaming Li, Jiexiang Xia, Molly Meng‐Jung Li   +13 more
wiley   +1 more source

Population Structure and Genetic Diversity of Italian Beef Breeds as a Tool for Planning Conservation and Selection Strategies

Animals, 2019
The aim was to investigate the population structure of eight beef breeds: three local Tuscan breeds under extinction, Calvana (CAL), Mucca Pisana (MUP), and Pontremolese (PON); three local unselected breeds reared in Sardinia, Sarda (SAR), Sardo Bruna ...
Maria Chiara Fabbri, Marcos Paulo Gonçalves de Rezende, Christos Dadousis, Stefano Biffani, Riccardo Negrini, Paulo Luiz Souza Carneiro, Riccardo Bozzi   +6 more
doaj   +1 more source