Results 51 to 60 of about 4,856 (294)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Asymptotic behavior and zero distribution of polynomials orthogonal with respect to Bessel functions [PDF]

open access: yes, 2015
We consider polynomials P_n orthogonal with respect to the weight J_? on [0,?), where J_? is the Bessel function of order ?. Asheim and Huybrechs considered these polynomials in connection with complex Gaussian quadrature for oscillatory integrals.
Deaño Cabrera, Alfredo   +5 more
core   +1 more source

Matrix quantum mechanics on S1/Z2

open access: yesNuclear Physics B, 2018
We study Matrix Quantum Mechanics on the Euclidean time orbifold S1/Z2. Upon Wick rotation to Lorentzian time and taking the double-scaling limit this theory provides a toy model for a big-bang/big crunch universe in two dimensional non-critical string ...
P. Betzios, U. Gürsoy, O. Papadoulaki
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Curves in the Minkowski plane and Lorentzian surfaces [PDF]

open access: yes, 2012
We investigate in this thesis the generic properties of curves in the Minkowski plane R2 1 and of smooth Lorentzian surfaces. The generic properties of curves in R2 1 are obtained by studying the contacts of curves in R2 1 with lines and pseudo-circles ...
SALOOM, AMANI
core  

Local moduli and singularities

open access: yes, 1988
This research monograph sets out to study the notion of a local moduli suite of algebraic objects like e.g. schemes, singularities or Lie algebras and provides a framework for this.
Laudal, Olav Arnfinn, Pfister, Gerhard
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A rational optimal block hybrid method for enhanced accuracy in solving Lane–Emden equations

open access: yesPartial Differential Equations in Applied Mathematics
This paper introduces a block hybrid method designed for the effective resolution of Lane–Emden equations, which are characterized as second-order boundary value problems incorporating a singularity at the origin.
Sandile Motsa   +3 more
doaj   +1 more source

Infinite distance networks in field space and charge orbits

open access: yesJournal of High Energy Physics, 2019
The Swampland Distance Conjecture proposes that approaching infinite distances in field space an infinite tower of states becomes exponentially light. We study this conjecture for the complex structure moduli space of Calabi-Yau manifolds.
Thomas W. Grimm   +2 more
doaj   +1 more source

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