Results 81 to 90 of about 6,762,995 (257)

Multidisciplinary nursing practice in a low-resource setting in Southeast Brazil

open access: yesHealthcare in Low-resource Settings
The various specializations available to nurses represent an investment geared toward providing more qualified patient care. However, little is known about the attitudes of specialized nurses toward multidisciplinarity.
Bruno Henrique Souza Izidório   +4 more
doaj   +1 more source

Does Local Financial Development Matter? [PDF]

open access: yes
We study the effects of differences in local financial development within an integrated financial market. To do so, we construct a new indicator of financial development by estimating a regional effect on the probability that, ceteris paribus, a ...
Luigi Guiso   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Local innovation systems in Poland - the beginning of the road

open access: yesMiscellanea Geographica: Regional Studies on Development, 2017
Local innovation systems (LIS) constitute a relatively new term as usually the discussion about the systemic approach to innovation has focused on the level of countries, and most of all - regions.
Dziemianowicz Wojciech   +2 more
doaj   +1 more source

Public sector restructuring and regional development: the impact of compulsory competitive tendering in the UK [PDF]

open access: yes, 2002
This paper contributes to the analysis of contemporary public sector restructuring in the UK through an evaluation of the impact of the introduction of compulsory competitive tendering (CCT) for the provision of local public services.
Patterson, A., Pinch, P. L.
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Deletion of Tfap2a in hepatocytes and macrophages promotes the progression of hepatocellular carcinoma by regulating SREBP1/FASN/ACC pathway and anti-inflammatory effect of IL10

open access: yesCell Death and Disease
The transcription factor AP-2α plays a crucial role in the control of tumor development and progression, and suppresses the proliferation and migration of hepatocellular carcinoma (HCC).
Zhiwei Li   +12 more
doaj   +1 more source

Glocalisation of global market forces and the repositioning of a peripheral Russian mining community [PDF]

open access: yes, 2015
Increasing globalisation and global market forces shape the development of resource peripheries in the Barents region. Foreign direct investments are concrete example of global market forces.
Suutarinen, Tuomas
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluating the Effectiveness of Rhizobium Inoculants and Micronutrients as Technologies for Nepalese Common Bean Smallholder Farmers in the Real-World Context of Highly Variable Hillside Environments and Indigenous Farming Practices

open access: yesAgriculture, 2019
Studies have shown the potential of rhizobia and associated micronutrients to enhance symbiotic nitrogen fixation in legumes. Tens of millions of smallholder farmers, however, farm on mountain hillsides in highly variable soil and microenvironments, with
Malinda S. Thilakarathna   +11 more
doaj   +1 more source

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