Results 271 to 280 of about 10,043,064 (337)
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Local Drug Delivery Techniques for Triggering Immunogenic Cell Death
Small Methods, 2023Immunogenic cell death (ICD), a dying state of the cells, encompasses the changes in the conformations of cell surface and the release of damage‐associated molecular patterns, which could initiate an adaptive immune response by stimulating the dendritic ...
En Ren +7 more
semanticscholar +1 more source
Self-assembly hydrogels of therapeutic agents for local drug delivery.
Journal of Controlled Release, 2022Advanced drug delivery systems are of vital importance to enhance therapeutic efficacy. Among various recently developed formulations, self-assembling hydrogels composed of therapeutic agents have shown promising potential for local drug delivery owing ...
Jun Zheng +8 more
semanticscholar +1 more source
ACS Applied Materials and Interfaces, 2022
Local drug delivery has become an effective method for disease therapy in fine organs including ears, eyes, and noses. However, the multiple anatomical and physiological barriers, unique clearance pathways, and sensitive perceptions characterizing these ...
Jiali Wang +9 more
semanticscholar +1 more source
Local drug delivery has become an effective method for disease therapy in fine organs including ears, eyes, and noses. However, the multiple anatomical and physiological barriers, unique clearance pathways, and sensitive perceptions characterizing these ...
Jiali Wang +9 more
semanticscholar +1 more source
Local drug delivery systems as therapeutic strategies against periodontitis: A systematic review.
Journal of Controlled Release, 2021Periodontitis is a chronic inflammation of the soft tissue surrounding and supporting the teeth, which causes periodontal structural damage, alveolar bone resorption, and even tooth loss.
Ying Wei +12 more
semanticscholar +1 more source
Local Drug Delivery to the Brain
Advanced Drug Delivery Reviews, 2002The controlled local delivery of antineoplastic agents by biodegradable polymers is a technique that allows for exposure of tumor cells to therapeutic doses of an active agent for prolonged periods of time while avoiding high systemic doses associated with debilitating toxicities.
Henry Brem, Paul P Wang
exaly +3 more sources
Prospection of Microfluidics for Local Drug Delivery
Current Drug Targets, 2022Abstract: Significant endeavors can be made to develop effective drug delivery systems. Nowa-days, many of these novel systems have gained attention as they focus primarily on increasing the bioavailability and bioaccessibility of several drugs to finally minimize the side effects, thus im-proving the treatment's efficacy.
Nimbagal R, Naveen +4 more
openaire +2 more sources
Peptide-based supramolecular hydrogels for local drug delivery.
Advanced Drug Delivery Reviews, 2021Peptide-based supramolecular hydrogels have shown great promise as drug delivery systems (DDSs) because of their excellent biocompatibility, biodegradability, biological function, synthetic feasibility, and responsiveness to external stimuli.
Zheng-Hao Zhang +3 more
semanticscholar +1 more source
Recrystallization of Adenosine for Localized Drug Delivery
Molecular Pharmaceutics, 2022Adenosine (ADO) is an endogenous metabolite with immense potential to be repurposed as an immunomodulatory therapeutic, as preclinical studies have demonstrated in models of epilepsy, acute respiratory distress syndrome, and traumatic brain injury, among others.
Ketki Y. Velankar +6 more
openaire +2 more sources
Current Opinion in Oncology, 2000
Intensive research efforts are now focused on the development of new strategies for more effective delivery of drugs to the central nervous system. These strategies include chemical modification of drugs, disruption of the blood-brain barrier, and utilization of alternative routes for drug delivery.
R I, Haroun, H, Brem
openaire +2 more sources
Intensive research efforts are now focused on the development of new strategies for more effective delivery of drugs to the central nervous system. These strategies include chemical modification of drugs, disruption of the blood-brain barrier, and utilization of alternative routes for drug delivery.
R I, Haroun, H, Brem
openaire +2 more sources
Otolaryngologic Clinics of North America, 2009
Topical drug delivery for sinonasal disorders is influenced by a variety of factors. Macroscopically (or anatomically), the ability of the drug to reach the appropriate region of the paranasal system is paramount. Delivery techniques, surgical state of the sinus cavity, delivery device, and fluid dynamics (volume, pressure, position) have a significant
Richard J, Harvey, Rodney J, Schlosser
openaire +2 more sources
Topical drug delivery for sinonasal disorders is influenced by a variety of factors. Macroscopically (or anatomically), the ability of the drug to reach the appropriate region of the paranasal system is paramount. Delivery techniques, surgical state of the sinus cavity, delivery device, and fluid dynamics (volume, pressure, position) have a significant
Richard J, Harvey, Rodney J, Schlosser
openaire +2 more sources