Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Success, challenges and prospects of decentralization in Africa: a systematic review
Cogent Social SciencesDecentralization remains a global development approach. African countries have been using decentralization by devolution to realize their development vision. This study assesses the success, challenges, and prospects of decentralization in Africa.
Rogers Rugeiyamu, Adam Msendo
doaj +1 more source
The Municipalities and INSPIRE – Any Connection?
Geoforum Perspektiv, 2014 On the surface, the municipalities are neither data owners nor data systems managers in connection with Denmark's reporting of data to INSPIRE. However, if you dig a little deeper in the actual data reports, you will see that the municipalities are ...
Inge Flensted
doaj +1 more source
Internationalisation Local Government in the Era of Bureaucracy Reform [PDF]
, 2013 Deteriorating performance of the bureaucracy in Indonesia are pessimistic effect on the readiness of the government apparatus to compete in the global dynamics that are supposed to give a greater role for the establishment of bureaucratic reform.
Fauzi, T. H. (Teddy)
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Engaging the local government in research & extension: The ACIAR-ICM-landcare experience
Annals of Tropical Research, 2017 Agricultural research and extension are important elements for improving agricultural production and food systems. It is said that the enhancement of traditional farming into science-based agriculture requires expeditious transfer of research results ...
Evy Elago-Carusos +2 more
doaj +1 more source
LOCAL GOVERNMENTS AND EVALUATION OF LOCAL GOVERNANCE TOOLS IN THE CONTEXT OF THE GOVERNANCE APPROACH
SOCIAL MENTALITY AND RESEARCHER THINKERS JOURNAL, 2020 The governance approach, which has serious reform proposals in public administration, has very critical principles such as transparency, accountability, rule of law, and participation. Depending on such principles, countries have been involved in various public reform movements in recent years.
openaire +2 more sources
Advancing a Performance Management Tool for Service Delivery in Local Government [PDF]
, 2023 I. M. Schoeman, James Chakwizira
openalex +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Exploring circularity in African cities: barriers and opportunities for meaningful action
Environmental Research: Infrastructure and SustainabilityAs African cities are on the frontline of a poly-crisis (Allouche et al 2023), the need for local action becomes more apparent. Local government authorities (LGAs) are uniquely positioned as crucial actors to address resource security, climate change ...
Zakiyya Atkins +3 more
doaj +1 more source