Results 51 to 60 of about 579,379 (266)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Unlocking value: a comprehensive costing study of primary health care service delivery in Tanzania

BMC Primary Care
Background Tanzania has long prioritized primary health care (PHC) as the pathway to achieving universal health coverage. However, greater, and more effective investments are needed to expand access to quality PHC services and further improve population ...
Federica Margini, Wilson Charles Mahera, Ntuli Kapologwe, James Tumaini Kengia, Dastan Mshana, Raymond Kiwesa, Gabrielle Appleford, Wendy Erasmus, Carl Schutte   +8 more
doaj   +1 more source

Review of the Commonwealth Local Government Good Practice Scheme

Commonwealth Journal of Local Governance, 2012
The overarching objective of the Commonwealth Local Government Good Practice Scheme (GPS) was to contribute towards the achievement of the Millennium Development Goals at the local level; there were four expected outputs: 1.
Rachael Duchnowski
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The Contribution of Family Businessesto Economic Growth: A Bibliometric Review

SAGE Open
The aim of this study is to review the body of literature on the contribution of family businesses to economic growth. The Scopus database was used to conduct the bibliometric analysis of the topic under discussion.
Wakara Ibrahimu Nyabakora
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Prevalence of fetal macrosomia and neonatal complications in a Nigerian suburban hospital: a five year study

Journal of Pediatric and Neonatal Individualized Medicine, 2018
Background: Fetal macrosomia has been the subject of several studies with a view to identifying the maternal risk factors and obstetric complications. There is a paucity of data on the neonatal complications.
Babatunde Kayode-Adedeji, Osayuwamen Egharevba, Hilda Omoregbee   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Commonwealth Local Government Forum: An Overview

Commonwealth Journal of Local Governance, 2008
The Commonwealth Local Government Forum (CLGF) was established in 1994, coinciding with rapid moves towards decentralisation at that time, especially in Commonwealth Africa.
Lucy Slack
doaj   +1 more source