Results 51 to 60 of about 4,084,636 (308)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Internationalisation Local Government in the Era of Bureaucracy Reform [PDF]
, 2013 Deteriorating performance of the bureaucracy in Indonesia are pessimistic effect on the readiness of the government apparatus to compete in the global dynamics that are supposed to give a greater role for the establishment of bureaucratic reform.
Fauzi, T. H. (Teddy)
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The Commonwealth Local Government Forum: An Overview
Commonwealth Journal of Local Governance, 2008 The Commonwealth Local Government Forum (CLGF) was established in 1994, coinciding with rapid moves towards decentralisation at that time, especially in Commonwealth Africa.
Lucy Slack
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Local Governance in Bangladesh: Policy and Strategy Framework
Commonwealth Journal of Local Governance, 2016 The author argued that the absence of a local governance policy is a priority governance problem in Bangladesh, which affects effective implementation of decentralisation policies and programmes sporadically undertaken from time to time.
Tofail Ahmed
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Local Government Actions to Prevent Childhood Obesity [PDF]
, 2009 Offers guidance on policy and programmatic actions local governments can take, with community input, to promote healthy eating and physical activity and to ensure equal opportunities for healthy living in low-income neighborhoods.
Annina Catherine Burns +2 more
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The 2011 Commonwealth Local Government Conference: Energising Local Economies: An Overview
Commonwealth Journal of Local Governance, 2011 In the current economic climate, creating the right environment for local enterprise, inward investment, and business and skills development, is an important factor in ensuring the prosperity and wellbeing of local communities.
Sue Rhodes
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source