Results 61 to 70 of about 4,084,636 (308)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Local government finances and financial management in Tanzania [PDF]
This report provides baseline data on local government finance and financial management in six councils in Tanzania: Bagamoyo District Council, Ilala Municipal Council, Iringa DC, Kilosa DC, Moshi DC, and Mwanza City Council.
Erasto Ngalewa +4 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The Demand for State and Local Government Employees [PDF]
, 1973 [Excerpt] The primary purpose of this paper is to present empirical estimates of the wage elasticities of demand for different categories of state and local government employees.
Ehrenberg, Ronald G
core +2 more sources
Commonwealth Local Government Forum’s support of Local Councils Associations in Pakistan
Commonwealth Journal of Local Governance, 2019 After a brief overview of the recent developments in the legal framework for local government in Pakistan, this paper summarises the objectives and activities to date of the Commonwealth Local Government Forum’s project ‘Strengthening the Associations of
Noor Akbar
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Report from the Controller and Auditor-General, Water and Roads: funding and management challenges [PDF]
The Office of the Auditor-General has investigated the state of the infrastructure, the maintenance done by local authorities, and what is needed to ensure the provision of roads and the “three waters” (water supply, wastewater, and stormwater) in the ...
Local Government and Environment Committee (New Zealand)
core
Intégrer les jeunes à la démocratie locale en Grande-Bretagne : tensions au New Labour
Lien Social et Politiques, 2002 La faible participation politique des jeunes et leur désenchantement vis-à-vis du débat politique constituent une question centrale, non seulement en Grande-Bretagne mais dans l’ensemble de l’Europe et des pays industrialisés.
Mike Geddes
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source