Results 51 to 60 of about 493,812 (272)
Yersinia pestis genomes reveal plague in Britain 4000 years ago
Extinct lineages of Yersinia pestis, the causative agent of the plague, have been identified in several individuals from Eurasia between 5000 and 2500 years before present (BP). One of these, termed the ‘LNBA lineage’ (Late Neolithic and Bronze Age), has
Pooja Swali+23 more
doaj +1 more source
When localizing the semidirect product of two groups, the effect on the factors is made explicit. As an application in Topology, we show that the loop space of a based connected CW-complex is a P-local group, up to homotopy, if and only if π1X and the free homotopy groups [S k-1, ΩX], k ≥ 2, are P-local.
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Localization for nonabelian group actions
Suppose $X$ is a compact symplectic manifold acted on by a compact Lie group $K$ (which may be nonabelian) in a Hamiltonian fashion, with moment map $ : X \to {\rm Lie}(K)^*$ and Marsden-Weinstein reduction $\xred = ^{-1}(0)/K$. There is then a natural surjective map $ _0$ from the equivariant cohomology $H^*_K(X) $ of $X$ to the cohomology $H ...
Jeffrey, L, Kirwan, F
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Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Since 2017, Italy has expanded the compulsory vaccination from 4 to 10 for those aged 0 to 16 years. Because of the great organizational effort required for the immunization services, minor attention was given to the vaccinations not included among the ...
Laura Serino+7 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
The Discontinuity Group of a Locally Bounded Homomorphism of a Lie Group into a Lie Group Is Commutative [PDF]
We prove that the discontinuity group of every locally bounded homomorphism of a Lie group into a Lie group is not only compact and connected, which is known, but is also commutative.
arxiv
A group homomorphism eta:A-> H is called a localization of A if every homomorphism phi:A-> H can be `extended uniquely' to a homomorphism Phi:H-> H in the sense that Phi eta = phi. This categorical concepts, obviously not depending on the notion of groups, extends classical localizations as known for rings and modules.
Göbel, Rüdiger, Shelah, Saharon
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It is concluded that faint members found in the vicinities of compact groups (CGs) are gravitationally bound with corresponding groups. All members of CGs, faint and bright, move preferentially in the direction of the elongation of the group. We suppose that the number of faint members may be much larger than previously assumed. These two circumstances
V. H. Chavushyan, Hrant M. Tovmassian
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Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source