Results 61 to 70 of about 6,229,024 (291)

Biomineralized Nanocomposite‐Integrated Microneedle Patch for Combined Brachytherapy and Photothermal Therapy in Postoperative Melanoma Recurrence and Infectious Wound Healing

Advanced Science
In the surgical management of malignant melanoma, incomplete tumor resection and large‐area cutaneous defects are major contributors to high locoregional recurrence and uncontrolled wound infections, resulting in poor prognosis and prolonged recovery ...
Peng Liu, Lu Hao, Jessica C. Hsu, Ming Zhou, Zhisheng Luo, Ying Peng, Weibo Cai, Shuo Hu   +7 more
doaj   +1 more source

Preclinical evaluation of uPAR-ICG-FVIOs for dual-mode imaging and magnetic hyperthermia therapy in pancreatic cancer

Frontiers in Pharmacology
BackgroundThis study presents a novel targeted nanomedicine for pancreatic cancer imaging and local magnetic hyperthermia therapy (MHT): urokinase plasminogen activator receptor (uPAR)-targeted, indocyanine green (ICG)-conjugated ferrimagnetic vortex ...
Tao Luo, Kelan Zhang, Chong Wu, Xiaolong Wu, Haojie Yang, Zhigang Chen, Fen Jiang   +6 more
doaj   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

A Technical Review On Hyperthermia [PDF]

, 2015
Hyperthermia has promising strategy to enhance apoptosis .The fundamental idea and the effects of heat oncancer cells are well known. However, the results obtained in therapy by hyperthermia (HT) alone have beenonly partially satisfactory.
D.Kaarthika1, Saranya.D2
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

efficacy of local hyperthermia in chemotherapy and /or radiation therapy for recurrences of hodgkin’s lymphom

Сибирский онкологический журнал, 2016
Results of local hyperthermia (LHT) in combined modality treatment of 25 patients with chemo-and radio-resistant recurrences of Hodgkin’s lymphoma were analyzed.
O. K. Kurpeshev, V. V. Pavlov, S. S. Shklyaev   +2 more
doaj  

Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans

Experimental Physiology, 2023
Heat and exercise therapies are recommended to improve vascular health across the lifespan. However, the haemodynamic effects of hyperthermia, exercise and their combination are inconsistent in young and elderly people.
Nuno Koch Esteves, Ashraf W. Khir, José González‐Alonso   +2 more
doaj   +1 more source

Clinical results of irradiation combined with local hyperthermia [PDF]

Cancer, 1983
This report updates a previous publication describing the experience at the Mallinckrodt Institute of Radiology with irradiation and hyperthermia in the treatment of superficial metastatic and recurrent malignant tumors. In a dose-seeking Phase I-II clinical study, a total of 101 lesions have been treated.
C A, Perez, G, Nussbaum, B, Emami, D, VonGerichten   +3 more
openaire   +2 more sources

Use of local hyperthermia as prophylaxis of fibrosis and modification in penile length following radical retropubic prostatectomy

, 2005
Objective: The aim of the study was to evaluate the effectiveness of local hyperthermia in reducing possible penile shortening following radical retropubic prostatectomy.
P. Vicini, PERUGIA, Giacomo, GENTILE, Vincenzo, LIBERTI, Marcello   +3 more
core   +1 more source