Results 81 to 90 of about 6,325,684 (293)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Local Ecological Knowledge Insights Into the Distribution and Activity Patterns of Temminck's Pangolin in Ruaha Landscape, Tanzania

Ecology and Evolution
Tanzania is home to three species of pangolins: Temminck's pangolin (Smutsia temminckii), giant ground pangolin (Smutsia gigantea), and white‐bellied pangolin (Phataginus tricuspis). However, distribution and habitat preferences have yet to be well known
Rose Peter Kicheleri, Courtney Hughes, Michael Honorati Kimaro, Charles Peter Mgeni, Nyemo Amos Chilagane, Hillary Thomas Mrosso, Simon Joshua Chidodo, Fenrick Filbert Msigwa, Elisante Azaeli Kimambo, Rajabu Joseph Kangile, George Bunyata Bulenga, Camille Warbington   +11 more
doaj   +1 more source

Pond fishing in the Congolese cuvette: a story of fishermen, animals, and water spirits

Revue d'ethnoécologie, 2016
In the Congo basin, fishing activities are a major source of protein and of income for many households. Fishermen combine a broad range of fishing methods adapted to the seasonality of the floodplain and the particular features of its habitats.
Marion Comptour, Sophie Caillon, Doyle McKey   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Local knowledge matters: understanding the decision-making processes of communities under climate change in Suriname

Frontiers in Climate
IntroductionTraditionally, local communities have relied on practical observations accumulated over extended periods to inform their decision-making.
Gwendolyn Smith, Mawie Chowenga, Jethro Karsters   +2 more
doaj   +1 more source

Degradación ambiental y periferia urbana: un estudio transdiciplinario sobre la contaminación en la región metropolitana de Buenos Aires

Ambiente & Sociedade, 2012
Este artículo presenta resultados de una investigación transdisciplinaria que combina el conocimiento local con saberes de las ciencias sociales y naturales con el propósito último de comprender y remediar los problemas socioambientales de barrios ...
Gustavo Curutchet, Silvia Grinberg, Ricardo A. Gutiérrez   +2 more
doaj   +1 more source

Knowledge Loss Managing Local Knowledge in Rural Uzbekistan [PDF]

, 2011
Knowledge loss is not a remote phenomenon, unique to one knowledge system. Rather we argue that the loss of knowledge is an issue for other knowledge systems as well. Knowledge loss is certainly a concern for anthropologists working on indigenous knowledge, fearful of ‘losing’ indigenous knowledge entirely as a result of modernisation (cf.
Wall, Caleb, Evers, Hans-Dieter
openaire   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Clusters and Knowledge Local Buzz, Global Pipelines and the Process of Knowledge Creation [PDF]

The paper is concerned with spatial clustering of economic activity and its relation to the spatiality of knowledge creation in various sorts of interactive learning processes. It questions the merit of the prevailing explanatory model where the realm of
Andersand Malmberg, Harald Bathelt, Peter Maskell   +2 more
core  

Application of existing knowledge: the only way to meet the MDG sanitation target in developing countries [PDF]

, 2008
The MDG sanitation target is, at current progress, unlikely to be met. The most important reasons for this are (1) that at local level, and in some countries at national level, engineers and planners simply do not know what sanitation systems are ...
Mara, D.D.
core