Results 91 to 100 of about 13,032,400 (279)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Supramolecular assembly and mechanical properties of dermis [PDF]

open access: yes, 2007
The present work is a part of a wider research project which aims at the in vitro tissues and biohybrid generation. The process of generating biological tissues requires benchmarks in order to define the optimal set of design and performance parameters ...
Ventre, Maurizio
core  

Quantifying the impact of oxidation on the mechanical properties of Alloy 718 using local mechanical testing techniques

open access: yesMaterials & Design
Despite excellent oxidative properties of the Alloy 718 Ni-based superalloy, long-term exposure to oxidative environments in service creates a chemical gradient in the sub-surface affected by oxidation.
Malo Jullien   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Mechanical Properties of Coronary Veins [PDF]

open access: yes, 2008
There are several publications available and experiments were done regarding to the vessel biomechanical properties. In the range we could find in vitro and in vivo assessments data for elasticity properties.
Dobránszky, János   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Direct Visualisation of the Depth-Dependent Mechanical Properties of Full-Thickness Articular Cartilage. [PDF]

open access: yes, 2012
The structural anisotropy of articular cartilage controls its deformation response. As proteoglycans and collagen vary with depth, simple uniaxial compression results in inhomogeneous deformation with distinct depth-dependent mechanical properties ...
Szarko, M, Xia, Y
core   +1 more source

Microstructure and Thermal Mechanical Behavior of Arc-Welded Aluminum Alloy 6061-T6

open access: yesJournal of Manufacturing and Materials Processing
In this study, the welding thermal cycle, as well as the microstructural and mechanical properties of welded AA6061-T6 plates, were studied. The plates were prepared and bead-on-plate welded using gas metal arc welding (GMAW). Numerical simulations using
Zeli Arhumah, Xuan-Tan Pham
doaj   +1 more source

Characterisation of Local Mechanical Properties in Living Tissues

open access: yes, 2017
The process of a single cell evolving into a complex organism results from a series of coordinated movements of cells and tissues, especially during early embryo development. Although a wealth of morphological data characterises the shapes and movements of cells in embryos, how these movements are driven, patterned and controlled, and how this ...
openaire   +2 more sources

Local mechanical properties of nanostructured polymer surfaces

open access: yes, 2022
2021 Spring Meeting of the European Materials Research Society (E-MRS) to be held as a VIRTUAL Conference from May 31st to June 3rd, 2021. (The VIRTUAL 2021 Spring Meeting will consist of parallel symposia with invited speakers, oral and poster presentations, assorted by plenary sessions and a number of workshops and training courses.) .-https://www ...
Martínez-Tong, Daniel E.   +4 more
openaire   +1 more source

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