Results 51 to 60 of about 5,469,672 (300)

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Osmaniye Yerel Basının Dijital Dönüşüm Çerçevesinde Eleştirel Ekonomi Politiği

İletişim Kuram ve Araştırma Dergisi
Araştırma, Osmaniye yerel basınının dijitalleşme sürecinde ekonomi politik yapısındaki değişimi ortaya koymayı amaçlamaktadır. Araştırmanın temel problemi, Osmaniye yerel basınının ekonomi politik yapısı dijitalleşmeyle birlikte değişime tabi olmuş mudur?
Gülsüm Şimşek
doaj   +1 more source

The sharp peak-flat trough pattern and critical speculation

, 1998
We find empirically a characteristic sharp peak-flat trough pattern in a large set of commodity prices. We argue that the sharp peak structure reflects an endogenous inter-market organization, and that peaks may be seen as local ``singularities ...
Roehner, B. M., Sornette, D.
core   +1 more source

Paedophiles in the community: inter-agency conflict, news leaks and the local press [PDF]

, 2005
This article explores the leaking of confidential information about secret Home Office plans to house convicted paedophiles within a local community (albeit inside a prison).
Adams, J., Anonymous editorial, Bellos, A., Byrne, C., Collier, R., Cottle, S., Critcher, C., Critcher, C., Critcher, C., Downing, J., Eldridge, J., Eldridge, J., Franklin, B., Greenslade, R., Howitt, D., Jenkins, P., Jewkes, Y., Kelly, L., Kemshall, H., Kitzinger, J., Kitzinger, J., Langer, J., Marr, A., Morris, S., Negrine, R., Parris, M., Press Complaints Commission, Rainer, R., Schlesinger, P., Silverman, J., Simon Cross, Slack, J., Slack, J., Slack, J., Soothill, K., Travis, A., Walker, D.   +36 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Formalism for the Subhalo Mass Function in the Tidal-limit Approximation

, 2003
We present a theoretical formalism by which the global and the local mass functions of dark matter substructures (dark subhalos) can be analytically estimated.
Jounghun Lee, Peacock J. A.
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Presse régionale et multisupports

Tic & Société, 2012
This article retraces the path followed  by a regional daily in France in diversifying its activities and enlisting its workers in the task of mastering a multichannel journalism.
Denis RUELLAN, Joël LANGONNE
doaj   +1 more source

Smallholder oil palm value chain in Cameroon: A case study from the department of Sanaga-Maritime [PDF]

, 2014
Cameroon has been producing palm oil for centuries but industrial scale production started around 1907 under the German colonisation with the development of estates and mills around the Littoral region (Sanaga-Maritime).
Abdelhakim, Tahani, Aboubakar Hayatou, Iyabano, Feintrenie, Laurène, Miaro, Ludovic   +3 more
core