Results 61 to 70 of about 7,662,913 (346)

Logistic optimization of the blood delivery routing problem in the Lower Southern region of Thailand

open access: yesEngineering and Applied Science Research, 2023
This study discusses a blood delivery routing problem faced by a regional blood centre (RBC). The RBC meets the requests of 21 hospitals for blood and blood products.
Kunanon Intapan   +4 more
doaj  

Local search inequalities

open access: yesDiscrete Optimization, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
LANCIA, Giuseppe   +2 more
openaire   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Improving modularity score of community detection using memetic algorithms

open access: yesAIMS Mathematics
With the growth of online networks, understanding the intricate structure of communities has become vital. Traditional community detection algorithms, while effective to an extent, often fall short in complex systems.
Dongwon Lee , Jingeun Kim, Yourim Yoon
doaj   +1 more source

No-Wait Job Shop Scheduling Using a Population-Based Iterated Greedy Algorithm

open access: yesAlgorithms, 2021
When no-wait constraint holds in job shops, a job has to be processed with no waiting time from the first to the last operation, and the start time of a job is greatly restricted. Using key elements of the iterated greedy algorithm, this paper proposes a
Mingming Xu   +2 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Scheduling Algorithms for a Hybrid Flow Shop under Uncertainty

open access: yesAlgorithms, 2020
In modern production systems, scheduling problems have to be solved in consideration of frequently changing demands and varying production parameters.
Christin Schumacher, Peter Buchholz
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Evolutionary Multi-objective Optimization for Multi-depot Vehicle Routing in Logistics

open access: yesInternational Journal of Computational Intelligence Systems, 2017
Delivering goods in an efficient and cost-effective way is always a challenging problem in logistics. In this paper, the multi-depot vehicle routing is focused. To cope with the conflicting requirements, an advanced multi-objective evolutionary algorithm
Xiaowen Bi, Zeyu Han, Wallace K. S. Tang
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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