Results 111 to 120 of about 1,132,072 (314)

Local Populations of Arabidopsis thaliana Show Clear Relationship between Photoperiodic Sensitivity of Flowering Time and Altitude

Frontiers in Plant Science, 2017
Adaptation of plants to local conditions that vary substantially within their geographic range is essential for seasonal timing of flowering, a major determinant of plant reproductive success.
Anna M. Lewandowska-Sabat, Siri Fjellheim, Jorunn E. Olsen, Odd A. Rognli   +3 more
doaj   +1 more source

THE MARKETING OF THE LOCAL COMMUNITIES AS A TOOL FOR SUPPORTING THEIR SUSTAINABLE DEVELOPMENT [PDF]

The sustainable development of the local communities represents a rathersensitive topic, that incorporates and integrates elements related to the both concepts:‘sustainable development‘, respectively ‘local communities‘. If an amount of marketing isadded,
Ioana Cecilia Popescu, Calin Veghes, Diana Dugulan   +2 more
core  

The spatial impact of local infrastructural investment in New Zealand

, 2010
In this paper we estimate the impact of local authority infrastructure spending in New Zealand using spatial econometric modeling, with the infrastructure spending itself endogenously determined.
Grimes, Arthur, Arthur Grimes, null null, Jacques Poot, William Cochrane, Poot, Jacques, McCann, Philip, Phillip McCann, Cochrane, William   +8 more
core   +1 more source

Sensitivity analysis and parameter estimation for distributed hydrological modeling: potential of variational methods [PDF]

, 2009
Variational methods are widely used for the analysis and control of computationally intensive spatially distributed systems. In particular, the adjoint state method enables a very efficient calculation of the derivatives of an objective function ...
Dartus, Denis, Saulnier, G.-M., D. Dartus, F.-X. Le Dimet, Castaings, William, Le Dimet, François-Xavier, G.-M. Saulnier, W. Castaings, Saulnier, Georges-Marie   +8 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Sensitivity analysis in linear models

Special Matrices, 2016
In this work, we consider the general linear model or its variants with the ordinary least squares, generalised least squares or restricted least squares estimators of the regression coefficients and variance.
Liu Shuangzhe, Ma Tiefeng, Liu Yonghui
doaj   +1 more source

Defining human contrast sensitivity and discrimination from complex imagery

, 2013
Shape, form and detail define image structure in our visual world. These attributes are dictated primarily by local variations in luminance contrast.
Gupta, G., Rana, H., S. Triantaphillidou, Triantaphillidou, S., H. Rana, J. Jarvis, G. Gupta, Jarvis, J.   +7 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Agreement and Sensitivity of the Acceleration–Velocity Profile Derived via Local Positioning System

Sensors
Sprint performance is commonly assessed via discrete sprint tests and analyzed through kinematic estimates modeled using a mono-exponential equation, including estimated maximal sprinting speed (MSS), relative acceleration (TAU), maximum acceleration ...
Mladen Jovanović, Adriano Arguedas-Soley, Dimitrije Cabarkapa, Håkan Andersson, Dóra Nagy, Nenad Trunić, Vladimir Banković, Répási Richárd, Sandor Safar, Laszlo Ratgeber   +9 more
doaj   +1 more source