Results 121 to 130 of about 1,132,072 (314)
Automated Sensitivity Analysis in Early Space Mission Design
, 2012 Concurrent Engineering in space mission design features several hundred design parameters provided by more than a dozen domain experts. The quality of the design strongly depends on the individual expertise of the people in the team, their experience and
Schaus, Volker +3 more
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Precipitation Sensitivity to Local Variations in Tropical Sea Surface Temperature
, 2018 The driving of tropical precipitation by the variability of the underlying sea surface temperature (SST) plays a critical role in the atmospheric general circulation.
He, Jie +5 more
core +2 more sources
Local Monte Carlo Simulation for the Reliability Sensitivity Analysis
, 2011 An efficient numerical technique, namely the Local Monte Carlo Simulation method, is presented to assess the reliability sensitivity in this paper.
Zhang Chun Tang, Zhen Zhou Lu, Da Wei Li
core +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Sensitivity analysis of the unconfoundedness assumption in observational studies [PDF]
In observational studies, the estimation of a treatment effect on an outcome of interest is often done by controlling on a set of pre-treatment characteristics (covariates). This yields an unbiased estimator of the treatment effect when the assumption of
de Luna, Xavier, Lundin, Mathias
core
, 2005 OBJECTIVES: To determine the value of computer-aided detection (CAD) for breast cancer screening. DESIGN: Two sets of mammograms with known outcomes were used in two studies.
Champness, J +9 more
core +1 more source
Local reliability based sensitivity analysis with the moving particles method
, 2020 Local reliability sensitivity methods aim at determining the partial derivatives of the failure probability or the reliability index with respect to model parameters.
Proppe, Carsten +2 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source