Results 51 to 60 of about 2,912,730 (295)

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Chronic morphine administration enhances nociceptive sensitivity and local cytokine production after incision

Molecular Pain, 2008
Background - The chronic use of opioids prior to surgery leads to lowered pain thresholds and exaggerated pain levels after these procedures. Several mechanisms have been proposed to explain this heightened sensitivity commonly termed opioid-induced ...
Angst Martin S, Qiao Yanli, Shi Xiaoyou, Liang DeYong, Yeomans David C, Clark J   +5 more
doaj   +1 more source

On Locality-Sensitive Orderings and Their Applications [PDF]

SIAM Journal on Computing, 2020
For any constant $d$ and parameter $\varepsilon > 0$, we show the existence of (roughly) $1/\varepsilon^d$ orderings on the unit cube $[0,1)^d$, such that any two points $p,q\in [0,1)^d$ that are close together under the Euclidean metric are "close together" in one of these linear orderings in the following sense: the only points that could lie ...
Chan, Timothy M., Har-Peled, Sariel, Jones, Mitchell   +2 more
openaire   +5 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Parity Measurement is Sufficient for Phase Estimation at the Quantum Cramer-Rao Bound for Path-Symmetric States

, 2012
In this letter, we show that for all the so-called path-symmetric states, the measurement of parity of photon number at the output of an optical interferometer achieves maximal phase sensitivity at the quantum Cramer-Rao bound.
Hwang Lee, J. J. Sakurai, Jonathan P. Dowling, Kaushik P. Seshadreesan, R. Shankar, Sejong Kim   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Supervised Multi-scale Locality Sensitive Hashing [PDF]

Proceedings of the 5th ACM on International Conference on Multimedia Retrieval, 2015
LSH is a popular framework to generate compact representations of multimedia data, which can be used for content based search. However, the performance of LSH is limited by its unsupervised nature and the underlying feature scale. In this work, we propose to improve LSH by incorporating two elements - supervised hash bit selection and multi-scale ...
Weng, Li, Jhuo, I-Hong, Shi, Miaojing, Sun, Meng, Cheng, Wen-Huang, Amsaleg, Laurent   +5 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Optical tracing of multiple charges in single-electron devices [PDF]

, 2014
Single molecules that exhibit narrow optical transitions at cryogenic temperatures can be used as local electric-field sensors. We derive the single charge sensitivity of aromatic organic dye molecules, based on first principles.
Faez, Sanli, Orrit, Michel, van der Molen, Sense Jan   +2 more
core   +3 more sources