Results 71 to 80 of about 1,132,072 (314)

Local opposite orientation preferences in V1: fMRI sensitivity to fine-grained pattern information

open access: yesScientific Reports, 2017
The orientation of a visual grating can be decoded from human primary visual cortex (V1) using functional magnetic resonance imaging (fMRI) at conventional resolutions (2–3 mm voxel width, 3T scanner).
Arjen Alink   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Motion processing deficits in migraine are related to contrast sensitivity

open access: yes, 2012
Background: There are conflicting reports concerning the ability of people with migraine to detect and discriminate visual motion. Previous studies used different displays and none adequately assessed other parameters that could affect performance, such ...
Hine, Trevor   +8 more
core   +1 more source

Local synchronization of resting-state dynamics encodes Gray's trait Anxiety [PDF]

open access: yes, 2013
The Behavioral Inhibition System (BIS) as defined within the Reinforcement Sensitivity Theory (RST) modulates reactions to stimuli indicating aversive events. Gray’s trait Anxiety determines the extent to which stimuli activate the BIS.
Tim Hahn   +11 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Local Buckling Check and Sensitivity Analysis Based on J-lay

open access: yesShiyou jixie, 2018
In view of the limitation of the local buckling failure evaluation formula of J-lay based on the natural catenary model, the Winkler foundation modeling is introduced for improvement. The entire suspension section is divided into two sections.
Wang Shuai
doaj  

On estimating local long-term climate trends [PDF]

open access: yes, 2013
Climate sensitivity is commonly taken to refer to the equilibrium change in the annual mean global surface temperature following a doubling of the atmospheric carbon dioxide concentration.
Chapman, S.C.   +9 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Which Communities should be afraid of Mobility? The Effects of Agglomeration Economies on the Sensitivity of Firm Location to Local Taxes [PDF]

open access: yes
This paper examines the effects of agglomeration economies (AE) on the sensitivity of firm location to tax differentials. An initial reading of the story suggests that, with AE, when a firm moves into a community attracted by a tax reduction, other firms
Jordi Jofre-Monseny, Albert Solé-Ollé
core  

The effect of modulating membrane lipid composition on the thermal sensitivity of tumour cells in culture [PDF]

open access: yes, 1989
The plasma membrane, which separates intracellular contents from extra cellular milieu, consists of a lipid bilayer comprising mainly phospholipids and cholesterol together with various functional proteins, which control the interaction of the cell with ...
Kingston, Catharine Alison
core  

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