Results 111 to 120 of about 2,690,059 (295)

RDDA: Rectified Discriminatory Delta-Adjust

IEEE Access
This paper introduces Rectified Discriminatory Delta-Adjust (RDDA), a novel methodology that enhances interpolation-based predictive modeling through adaptive sensitivity parameters.
Ziad F. Doughan, Sari S. Itani
doaj   +1 more source

An Alternative Sensitivity Approach for Longitudinal Analysis with Dropout

Journal of Probability and Statistics, 2019
In any longitudinal study, a dropout before the final timepoint can rarely be avoided. The chosen dropout model is commonly one of these types: Missing Completely at Random (MCAR), Missing at Random (MAR), Missing Not at Random (MNAR), and Shared ...
Amal Almohisen, Robin Henderson, Arwa M. Alshingiti   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Sensitivity analysis of a mathematical model for malaria transmission accounting for infected ignorant humans and relapse dynamics

Frontiers in Applied Mathematics and Statistics
This article presents and analyzes a deterministic model for malaria transmission that incorporates infected individuals who are unaware of their infectious status (ignorant infected humans) and accounts for relapse dynamics.
Getahun Tadesse Haile, Purnachandra Rao Koya, Fekadu Mosisa Legesse   +2 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The International Competitiveness of the Table Egg Industry of Trinidad and Tobago [PDF]

The research undertaken was four-fold. First, to investigate whether government policy provides protection and by extension, incentives for the local table egg farmers to remain in production. To do so, EPC's for all commercial farms in the industry were
Harry, Edric
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Existence, Stability and Sensitivity Analysis of Lyme Disease Using Caputo Fractional Dynamical Systems

Fractal and Fractional
In this article, mathematical modeling and stability analysis of Lyme disease and its transmission dynamics using Caputo fractional-order derivatives is presented.
Kashif Ullah, Nayyar Mehmood, Abdullah Eqal Al-Mazrooei, Jamshaid Ahmad   +3 more
doaj   +1 more source

Local sensitivity analysis of a supercritical extraction model

The Canadian Journal of Chemical Engineering
Abstract This study investigates the process of chamomile oil extraction from chamomile flowers. A parameter‐distributed model, consisting of a set of partial differential equations, was used to describe the governing mass transfer phenomena between solid and fluid phases under supercritical conditions using carbon dioxide as the ...
Oliwer Sliczniuk, Pekka Oinas
openaire   +1 more source