Results 101 to 110 of about 1,015,464 (310)
Climate Adaptation decision support Tool for Local Governments: CATLoG [PDF]
, 2013 The Intergovernmental Panel on Climate Change (IPCC), the globally-recognised reference body for climate-related research, describes warming of the climate system as ‘unequivocal’.
Supriya Mathew +2 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
PLoS ONE, 2018 The hemostatic response involves blood coagulation and platelet aggregation to stop blood loss from an injured blood vessel. The complexity of these processes make it difficult to intuit the overall hemostatic response without quantitative methods ...
Kathryn G Link +6 more
doaj +1 more source
Sensitivity analysis of the unconfoundedness assumption in observational studies [PDF]
In observational studies, the estimation of a treatment effect on an outcome of interest is often done by controlling on a set of pre-treatment characteristics (covariates). This yields an unbiased estimator of the treatment effect when the assumption of
de Luna, Xavier, Lundin, Mathias
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Comparing sensitivity analysis methods to advance lumped watershed model identification and evaluation [PDF]
Hydrology and Earth System Sciences, 2007 This study seeks to identify sensitivity tools that will advance our understanding of lumped hydrologic models for the purposes of model improvement, calibration efficiency and improved measurement schemes. Four sensitivity analysis methods were tested: (
Y. Tang +3 more
doaj
Error Estimation for the Linearized Auto-Localization Algorithm
Sensors, 2012 The Linearized Auto-Localization (LAL) algorithm estimates the position of beacon nodes in Local Positioning Systems (LPSs), using only the distance measurements to a mobile node whose position is also unknown.
Fernando Seco +3 more
doaj +1 more source
Local Minimizers in micromagnetics and related problems
, 2002 Let $\Omega \subset{\bf R}^3$ be a smooth bounded domain and consider the energy functional ${\mathcal J}_{\varepsilon} (m; \Omega) := \int_{\Omega} \left ( \frac{1}{2 \varepsilon} |Dm|^2 + \psi(m) + \frac{1}{2} |h-m|^2 \right) dx + \frac{1}{2} \int_ ...
J M Ball (16079657) +12 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source