Results 41 to 50 of about 2,690,059 (295)

Global stability dynamics and sensitivity assessment of COVID-19 with timely-delayed diagnosis in Ghana

open access: yesComputational and Mathematical Biophysics, 2022
In this paper, we study the dynamical effects of timely and delayed diagnosis on the spread of COVID-19 in Ghana during its initial phase by using reported data from March 12 to June 19, 2020. The estimated basic reproduction number, ℛ0, for the proposed
Moore Stephen E.   +4 more
doaj   +1 more source

Testing of NH3/H2 and NH3/syngas combustion mechanisms using a large amount of experimental data

open access: yesApplications in Energy and Combustion Science, 2023
A possible solution to improve the combustion properties of ammonia is to blend it with other fuels. Two of the most usually used co-fuels are hydrogen and syngas (H2/CO). To investigate the chemistry of the co-combustion with these fuels, a large amount
András György Szanthoffer   +4 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Methodological Framework for Optimizing Palm-Based Soap Formulations Using Deep Neural Networks

open access: yesIEEE Access
This paper proposes a design framework for palm-based soap formulations that predicts key properties, melting point (MP), fatty acid profile, and cost, with high fidelity and direct applicability in industrial plants.
Freddy Marcillo Rivadeneira   +1 more
doaj   +1 more source

No. 09: Comparing Household Food Security in Cities of the Global South through a Gender Lens [PDF]

open access: yes, 2017
Understanding the determinants of urban food insecurity requires sensitivity to local cultural contexts and taking into account a globally relevant framework for analysis.
Caesar, Mary, Riley, Liam
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Local and Global Sensitivity Analysis of Cr (VI) Geogenic Leakage Under Uncertain Environmental Conditions

open access: yesWater Resources Research, 2018
We focus on the joint application of local and global sensitivity analyses to characterize propagation of model parameter uncertainties to outputs of subsurface water geochemical models.
G. Ceriotti   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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