Results 51 to 60 of about 2,690,059 (295)

Differential and Time-Discrete SEIRS Models with Vaccination: Local Stability, Validation and Sensitivity Analysis Using Bulgarian COVID-19 Data

Mathematics, 2023
Bulgaria has the lowest COVID-19 vaccination rate in the European Union and the second-highest COVID-19 mortality rate in the world. That is why we think it is important better to understand the reason for this situation and to analyse the development of
Svetozar Margenov, Nedyu Popivanov, Iva Ugrinova, Tsvetan Hristov   +3 more
doaj   +1 more source

Local stability analysis and eigenvalue sensitivity of reacting bluff-body wakes [PDF]

, 2016
This paper presents an experimental and theoretical investigation of high-Reynolds-number low-density reacting wakes near a hydrodynamic Hopf bifurcation.
Emerson, B, Juniper, MP, Lieuwen, T
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Local and global sensitivity analysis for railway upgrading between hydrogen fuel cell and electrification

High-Speed Railway
In the field of rail transit, the UK Department of Transport stated that it will realize a comprehensive transformation of UK railways by 2050, abandoning traditional diesel trains and upgrading them to new environmentally friendly trains.
Yizhe Zhang, Zhongbei Tian, Kangrui Jiang, Stuart Hillmansen, Clive Roberts   +4 more
doaj   +1 more source

SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool

BMC Bioinformatics, 2008
Background It has long been recognized that sensitivity analysis plays a key role in modeling and analyzing cellular and biochemical processes. Systems biology markup language (SBML) has become a well-known platform for coding and sharing mathematical ...
Rundell Ann E, Zheng Yanan, Zi Zhike, Klipp Edda   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Decoherence from a Chaotic Environment: An Upside Down "Oscillator" as a Model

, 2003
Chaotic evolutions exhibit exponential sensitivity to initial conditions. This suggests that even very small perturbations resulting from weak coupling of a quantum chaotic environment to the position of a system whose state is a non-local superposition ...
A.O. Caldeira, B.L. Hu, D. Monteoliva, D. Monteoliva, G. Usaj, H. Kubotani, H.M. Pastawski, J.R. Anglin, M.A. Sakagami, P. Bianucci, P. Jacquod, P. Jacquod, P.A. Miller, P.A. Miller, P.R. Levstein, R.A. Jalabert, R.J. Glauber, Robin Blume-Kohout, S. Habib, T. Gorin, T. Prosen, W.G. Unruh, W.H. Zurek, W.H. Zurek, W.H. Zurek, W.H. Zurek, W.H. Zurek, W.H. Zurek, Wojciech H. Zurek, Z.P. Karkuszewski   +29 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Collapse of an ecological network in Ancient Egypt [PDF]

, 2014
The dynamics of ecosystem collapse are fundamental to determining how and why biological communities change through time, as well as the potential effects of extinctions on ecosystems.
Dominy, Nathaniel J., Gross, Thilo, Guimarães Jr., Paulo R., Koch, Paul L., Pires, Mathias M., Rudolf, Lars, Yeakel, Justin D.   +6 more
core   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source